C-反应蛋白在不同程度急性心梗患者中的相关性研究  

Relationship between C reactive protein level and cardiac function in patients with acute myocardial infarction

作　　者：曹琳[1] 陈雷旻[1] 张晔凡[1] 陈炼[1] 楼丽娜[1] 

机构地区：[1]上海市第二人民医院心内科,上海200011

出　　处：《现代生物医学进展》2011年第5期890-892,共3页Progress in Modern Biomedicine

摘　　要：目的:探讨C-反应蛋白(CRP)在急性心肌梗死患者中的变化及与心功能之间的关系。方法:选取121例急性心肌梗死(AMI)患者和50例健康对照者,酶联免疫吸附法(ELISA)检测血清C-反应蛋白(CRP)和B型钠尿肽(BNP)。结果:AMI患者血清CRP显著高于健康对照,AMI伴心功能III,IV级者血清BNP、CRP显著高于AMI伴心功能I,II级者。结论:血清CRP对于急性心肌梗死患者的心功能重要参考指标。Objective：To investigate the Correlations between serum high sensitivity C reactive protein（CRP） level and cardiac functions in acute myocardial infarction.Methods：The serum levels of CRP and BNP were examined in 50 healthy adults and 121 patients with AMI.Left ventricular ejection fraction（LVEF） was measured by echocardiography and the levels of CRP and BNP were detected by ELISA.Results：Compared with control group,AMI patients had high serum levels of CRP and BNP（P0.01）.The serum levels of CRP and BNP of Killip III and IV class is higher than those of Killip I and II class CRP（P0.01）.Conclusion：Just as BNP,The serum CRP level can be a sensitive index in the patients with acute myocardial infarction.

关 键 词：急性心肌梗塞 C-反应蛋白 心脏功能 

分 类 号：R542.22[医药卫生—心血管疾病]