HPLC测定道地产地和主产地茅苍术中β-桉叶醇及其他成分的含量  

Determination of β-eudesmol and Other Compositions in Rhizome of Atractylodes lancea by HPLC

作　　者：张贝贝[1] 方婧[1] 许海玉[1] 李德凤[1] 杨洪军[1] 王祝举[1] 唐力英[1] 杨岚[1] 张东[1] 付梅红[1] 

机构地区：[1]中国中医科学院中药研究所,北京100700

出　　处：《中国实验方剂学杂志》2011年第8期116-118,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：中国中医科学院基本科研业务费自主选题项目(Z02063)

摘　　要：目的:通过测定道地产地和主产地茅苍术中有效成分及其他成分的含量,综合评价茅苍术的药材品质。方法:采用HPLC对不同产地的茅苍术中的β-桉叶醇、苍术素、苍术素醇和苍术内酯Ⅱ进行含量测定。结果:不同产地的茅苍术中成分的含量差异显著,各地的茅苍术药材质量存在较大差异。β-桉叶醇和苍术素醇含量最高的是湖北英山的野生品;苍术素和苍术内酯Ⅱ含量最高的产地是江苏茅山。结论:综合考虑茅苍术中苍术素、β-桉叶醇、苍术素醇和苍术内酯Ⅱ主产地的茅苍术的质量要比道地产地茅苍术的质量优,该结果为茅苍术的产业化发展提供依据。Objective：By determining the active compositions and other compositions in rhizome of Atractylodes lancea from geoherbs and herbs in main producing areas in order to synthetically evaluate the quality of them.Method：β-eudesmol,atractylon,atractylodinol and atractylenolide Ⅱ in rhizome of A.lancea in different regions were determined by HPLC.Result：There were great differences in content and quality among different regions of A.lancea.The highest content of β-eudesmol and atractylodinol was found in wild products grown in Yingshan city Hubei Province,while the highest content of atractylon and atractylenolideⅡ was found in maoshan city Jiangsu province.Conclusion：The quality in the main origins was better than that in authentic origin from the content determination of β-eudesmol,atractylon,atractylodinol and atractylenolide Ⅱ in different places,which provide the basis for industrial development of lancea.

关 键 词：茅苍术 Β-桉叶醇 苍术素 苍术素醇 苍术内酯Ⅱ 高效液相色谱法 含量测定 

分 类 号：R284.1[医药卫生—中药学]