秦皇岛市2010年麻疹和风疹疑似病例血清学检测结果  

Results of Serological Detection in Suspected Cases of Measles and Rubella in Qinhuangdao City in 2010

作　　者：刘兰吉[1] 张海滨[1] 罗永松[1] 

机构地区：[1]河北省秦皇岛市疾病预防控制中心微生物室,066000

出　　处：《职业与健康》2011年第7期F0002-F0002,F0003,共2页Occupation and Health

摘　　要：目的对2010年秦皇岛市麻疹疑似病例进行IgM抗体检测,分析麻疹流行病学特征,为麻疹计划免疫提供科学依据。方法采用酶联免疫捕获试验(Capture-ELISA)方法,检测麻疹疑似病例急性期血清麻疹IgM抗体、风疹IgM抗体。结果 2010年该市共检测麻疹疑似病例210例,其中麻疹IgM抗体阳性135例,风疹IgM抗体阳性30例。麻疹、风疹发病主要集中在5、6月份,麻疹共发病89例,占65.93%。风疹共发病25例,占83.33%。麻疹病例以1岁及以下组最多(69例,51.11%)。结论 4岁以下儿童为麻疹的高发人群,其中1岁及以下婴儿患病率最高,提示母体抗体的保护作用不足。疑似麻疹的病例中有一部分是风疹病例,因此进行IgM抗体检测可以为科学鉴别麻疹与风疹,及时有效控制麻疹疫情提供依据。[ Objective] To detect the IgM antibody in measles suspected cases in Qinbuangdao City in 2010, analyze the epidemio- logical characteristics of measles, and provide the scientific basis for measles immunization. [ Methods ] The serum IgM antibodies of measles and rubella were detected in measles suspected cases during acute period with capture enzyme linked immunosorbent assay （ Capture-ELISA）. [ Results] In 2010, 210 measles suspected cases were detected, and there were 135 measles IgM positive cases and 30 rubella IgM positive cases. Most of measles and rubella cases occurred in May and June, there were 89 cases of measles and 25 cases of rubella, which accounted for 65.93% and 83.33% respectively. The incidence of measles in children under one year of age was the highest {69 cases, 51.11% }. [ Conclusion ] Children under 4 years of age are the high-risk population of measles, and the prevalence rate of infants under one year of age is the highest, which indicates the protective effect from maternal antibody is insufficient. There are some rubella cases among measles suspected cases. The detection of IgM antibody is helpful to scientific distin- guish rubella from measles, and can provide the basis for effective control of measles outbreaks.

关 键 词：麻疹 风疹疑似病例 流行特征 IGM抗体 

分 类 号：R181.3[医药卫生—流行病学]