肠道病毒感染在小儿原发性肠套叠发病中的作用  

The role of enterovirus infection in children with idiopathic intussusception

作　　者：赵长安[1] 周红[2] 李仲智[2] 杨永弘[2] 

机构地区：[1]广东省妇幼保健院,广州510010 [2]首都医科大学附属北京儿童医院,北京100045

出　　处：《中国妇幼卫生杂志》2011年第2期64-66,共3页Chinese Journal of Women and Children Health

基　　金：国家自然科学基金资助项目(编号:30371474)

摘　　要：目的探讨肠道病毒感染在儿童肠套叠发病中的地位,为临床预防和减少肠套叠的发生提供理论依据。方法研究组为首都医科大学附属北京儿童医院2002年9月至2003年12月确诊的72例原发性肠套叠患儿,以时间、年龄及性别匹配的78例健康儿童为对照组,分别采集粪便标本。使用肠道病毒公用引物进行逆转录聚合酶链反应,检测粪便标本中的肠道病毒。结果研究组和对照组肠道病毒的阳性率分别为2.8%(2/72)和3.8%(3/78),两组间差异无统计学意义(P>0.05)。结论肠道病毒感染与原发性肠套叠之间可能无相关性。Objective To find the relationship among enterovirus infection and idiopathic intussusception. Methods Fecal and blood samples were collected from 72children with idiopathic intussusception that was observed in Beijing Children＇s Hospital. Additional samples of 78 time-age-and sex-matched healthy children collected from September 2002 to December 2003 were enrolled in this study as controls. Results transcriptase polymerase chain reaction（RT-PCR） were used to detect rotavirus and enterovirus in fecal samples respectively. Results Enterovirus was observed in 2 of 72 patients （2.8%） and 3 of 78 control children （3.8%）. There was no significant difference between two groups （P0.05）. Conclusions The data of the present study suggest that enteroviral infection may not be association with intussusception.

关 键 词：肠道病毒 儿童 肠套叠 

分 类 号：R726.5[医药卫生—儿科]