应用Embophere微球栓塞治疗急性大咯血的临床研究  

Application of Embosphere in the treatment of severe hemoptysis:a retrospective of 27 cases

作　　者：李春龙[1] 金泳海[1] 邹建伟[1] 孙鸽[1] 沈健[1] 杨超[1] 倪才方[1] 

机构地区：[1]苏州大学附属第一医院介入科,江苏215006

出　　处：《当代医学》2011年第5期73-74,共2页Contemporary Medicine

摘　　要：目的研究Embophere微球在支气管动脉栓塞治疗急性大咯血中的价值。资料与方法回顾分析2009年5月～2009年12月,27例急性大咯血患者行Emophere微球栓塞治疗的临床资料。予选择性支气管动脉造影后,用微导管超选择插至支气管动脉,注入不同规格的Embophere微球栓塞末梢支气管动脉,并继以明胶海绵颗粒加强栓塞,观察治疗有效率及并发症情况。结果 26例获显著疗效(96.3%),其中即刻止血23例(85.2%)、1d～3d内咯血停止3例(11.1%)。1例(3.7%)即刻出血有缓解,但1周后复发,行手术治疗。随访(6～9)个月,除以上1例手术切除外,无复发。6例术后出现胸痛,均在一周内缓解,未见截瘫等严重并发症。结论 Embophere微球在支气管动脉栓塞治疗急性大咯血安全、有效,值得临床推广应用。Objective To evaluate the value of application of Embosphere microphere in bronchial artery embolization for severe hemoptysis. Materials and methods Twenty-seven patients of severe hemoptysis were treated with embolization consecutively between May and December, 2009. After selective bronchial arteriography, micro-catheters were employed to eannulate the distal end of bronchial arteriy, then the Embosphere was injected followed by gelatine sponge particles. Its efficacy and complications were analyzed retrospectively. Result In 27 cases, 26 （96.3%） had significant effect, in which 23 of bleeding ceased instantly after embolization and 3 in 1-3 days after embolization. One received surgical operation because of recurring after 1 week, even though immediate alleviation of bleeding. In follow-up period of 6-9 months, no one of hemoptysis recurred except for the one mentioned above. Chest pain was observed in 6 patients after embolization, which was relieved in 1 week. No severe complications such as paraplegia happened. Conclusion Bronchial artery embolization with the application of Embosphere is effective and safe in the treatment of severe hemoptysis.

关 键 词：咯血 支气管动脉 栓塞 Embophere微球 

分 类 号：R56[医药卫生—呼吸系统]