无溶剂合成α-溴-4-甲氧基苯乙酮  

Synthesis of α-bromo-4-methoxylacetophenone under solvent-free

作　　者：王小利[1] 刘明星[1] 王贤文[1] 苏江涛[1] 林松[1] 

机构地区：[1]湖北工业大学生物工程学院,湖北武汉430068

出　　处：《化学试剂》2011年第4期377-378,共2页Chemical Reagents

摘　　要：在无溶剂条件下,将4-甲氧基苯乙酮和1,2-二吡啶-二(三溴)乙烷(DPTBE)混合室温研磨成功制备了标题化合物,产率89%。经质谱、核磁、红外和元素分析等手段鉴定了目标分子的结构。该法与传统方法比较具有无有机溶剂污染、反应速度快和产率高等优点。The α-bromo-4-methoxylacetophenone with the yield of 89% was synthesized by the grinding reaction of 4-methoxylacetophenone and 1,2-dipyridiniumditribromide-ethane（DPTBE） under solvent-free and room temperature.The molecule structure of synthesized compound was identified by MS,IR,1HNMR and elemental analysis.The advantages of this menthod are no organic solvent pollution,elevating reaction rate and high yield compared with traditional method.

关 键 词：无溶剂 研磨 α-溴-4-甲氧基苯乙酮 

分 类 号：O621.3[理学—有机化学]