新型双核阳离子离子液体催化合成庚二酸二乙酯  

SYNTHESIS OF DIETHYL PIMELATE BY A NEW IONIC LIQUID WITH BINUCLEAR CATIONS

作　　者：赵振贵[1] 李华[1] 赵蕾[1] 

机构地区：[1]郑州大学化工与能源学院,河南郑州450001

出　　处：《精细石油化工》2011年第2期72-74,共3页Speciality Petrochemicals

摘　　要：制备一种新型强酸性双核阳离子离子液体N,N′-烷基-(3-甲基)-二咪唑硫酸氢盐,用于1,7-庚二酸和乙醇的酯化反应,通过简单的处理就可以实现产品和离子液体的分离。采用单因素和正交实验考察了催化剂用量、反应时间、反应温度和醇酸比对反应的影响,最佳反应条件为:n(C_2H_5OH):n(C_7H_(12)O_4)=3:1、催化剂用量11.1%、反应时间5.5h、反应温度108℃,庚二酸二乙酯收率为97.81%。离子液体重复使用5次,庚二酸二乙酯的收率均在96.65%以上。A new ionic liquid with strong acid binuclear cations, namely, N,N＇-alkyl-（3-methyl）-diimidazolium hydrogen sulfate, is used for the esterification of 1,7-pimelic acid and ethanol. The products and ionic liquids can be separated by simple methods. The esterification products could be easily separated in high yield from the reaction system via simple phase separation. The effects of the reaction conditions on the reaction results, such as the amount of catalyst, molar ratio of acid and alcohol, re action time, etc, were examined and the optimal conditions were obtained through orthogonally designed experiments based on single-factor experiments. The optimal conditions were found as follows： n（C2H5OH） ： n（CTH12O4）=3 ： 1, 11. 1% catalyst , 5.5 h and 108℃. Under the optimal reaction conditions, the yield was 97.81%. Separated from the products, the ionic liquids could be reused for 5 times and the yields were up to 96.65%. Compared with the concentrated sulfuric acid, the traditional catalyst, the ionic liquids have the advantages of excellent stability, less pollution, less side re action, good repeatability, and no organic solvent being required as water carrying agent.

关 键 词：离子液体 庚二酸二乙酯 催化合成 单因素实验 正交实验 

分 类 号：TQ426.94[化学工程]