宫血宁胶囊预防放置宫内节育器后子宫异常出血的效果  

Effects of Gongxuening Capsules on prevention of abnormal uterine bleeding after IUD insertion

作　　者：张胜利[1] 吴尚纯[2] 

机构地区：[1]福建中医药大学管理学院,福州350001 [2]国家人口计生委科学技术研究所

出　　处：《中国计划生育学杂志》2011年第4期202-205,共4页Chinese Journal of Family Planning

摘　　要：目的:分析宫血宁胶囊预防放置IUD致子宫异常出血的效果。方法:应用meta分析方法的固定效应模型,对国内1990～2010年采用宫血宁胶囊预防放置IUD致出血副反应,并以空白或安慰剂对照的随机分组研究进行定量合并分析。结果:治疗组1168例患者中87例经量增多或经期延长,对照组1168例患者中392例经量增多或经期延长。合并优势比(OR)=6.79,95%置信区间(CI)为5.25～8.78,两者间差异有统计学意义(合并效果检验统计量Z=14.58,P<0.001)。结论:宫血宁胶囊预防放置IUD出血副反应的效果肯定,可以显著减少经量增多和经期延长的发生。Objective：To explore effects of Gongxuening Capsules on preventing abnormal uterine bleeding after intrauterine device（IUD）insertion.Methods：A fixed-effect model of meta-analysis of six literatures published between 1990 and 2010,involving in a randomized placebo-controlled trail（or with blank as the control）,was used to evaluate effects of Gongxuening Capsules.Results：Eighty-seven of 1 168 women using Gongxuening Capsules and 392 women in the control group experienced menorrhagia or menostaxis,showing a statistical significance（Z=14.58,P0.001）.The total odds ratio was 6.79（95%CI：5.25,8.78）.Conclusion：Gongxuening Capsules can significantly reduce the incidence of menorrhagia and menostaxis.

关 键 词：宫内节育器 出血 宫血宁 Meta分析 

分 类 号：R169.4[医药卫生—公共卫生与预防医学]