肿瘤病人舌苔变化与唾液中人上皮生长因子的关系研究  

Study on the Relation Between Tongue Coating and Saliva h-EGF Content of Tumor Patients

作　　者：詹瑧[1] 郝晋丰 汪红[3] 马永华 

机构地区：[1]南京中医药大学基础医学院,江苏南京210029 [2]江苏省南京市钟山医院,江苏南京210014 [3]南京中医药大学附属医院,江苏南京210029

出　　处：《南京中医药大学学报》1999年第6期350-351,共2页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：江苏省教委自然科学基金!资助项目 (960 60 )

摘　　要：目的 :研究肿瘤病人舌苔变化与唾液中人上皮生长因子h -EGF含量的关系。方法 :采用1 2 5 I放射免疫分析法 (RIA )。结果 :15 2例肿瘤病人唾液中h -EGF含量为 (4.0 70± 1.0 ) μg L ,明显高于正常人 (3.0 71±1.7) μg L(P <0 .0 1) ,其中 10 2例厚苔者 (占 6 7.1% )的h -EGF含量为 (4.2 70± 1.7) μg L ,也明显高于 5 0例薄苔者 (占 32 .9% )的h -EGF含量 (3.6 91± 1.2 ) μg L (P <0 .0 1)。 结论 :唾液中h -EGF含量与肿瘤病人舌苔增厚密切相关。OBJECTIVE:To investigate the relation between tongue coating and saliva h-EGF content of tumor patients.METHOD:The method of 125 I radioimmunoassay(RIA) was applied. RESULT: Among 152 tumor cases, there were 102 cases(67.1%) with thick coating and 50 cases(32.9%) with thin coating. The saliva h-EGF content of tumor patients(4.070±1.0 μg/L) was obviously higher than that of normal person(3.071±1.7 μg/L)( P <0.01), and the h-EGF content of patients with thick coating(4.270±1.7 μg/L) was apparently higher than that of patients with thin coating(3.691±1.2 μg/L)( P <0.01). CONCLUSION:For tumor patients, there is a close relation between saliva h-EGF content and tongue coating thickness.

关 键 词：肺癌 舌苔 人上皮生长因子 放射免疫分析 

分 类 号：R273.42[医药卫生—中西医结合] R241.25[医药卫生—中医肿瘤科]