糖尿病与结直肠癌关系的研究  

An ecological association between the prevalence of Diabetes Mellitus and the incidence of colorectal cancer

作　　者：张旭慧[1] 王强[1] 盛萍[1] 虞龙[1] 沈卫星[1] 张磊[1] 

机构地区：[1]杭州市疾病预防控制中心,杭州310021

出　　处：《中国卫生检验杂志》2011年第4期888-889,895,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的:探讨糖尿病患病与结直肠癌发病之间的关系。方法:采用生态学研究的方法,对全世界170个国家和地区的糖尿病患病和结直肠癌发病的资料进行相关性和线性回归分析。结果:男、女性糖尿病患病率和结直肠癌的发病率均呈现正相关的关系,相关性研究表明,等级相关系数分别为0.534和0.597(P值均小于0.001)。结论:糖尿病患病可能与结直肠癌发病危险性有关。Objective：To study the association between the prevalence of diabetics mellitus（DM） and colorectal incidence（CRC）.Methods： The data of the prevalence of DM and incidence of CRC in 170 countries were collected and correlation relation was analyzed between DM and CRC.Results： The prevalence of DM was positively associated with the incidence of CRC.The spearman＇s coefficients of correlation（rs） in male and female were 0.534 and 0.597（Both of P value 0.001）,respectively.The prevalence of DM is a significant positive predicator of CRC incidence in male and female with a decisive coefficient（R2） of 0.194 and 0.332 and a slope（βi） of 20.25 and 21.81,respectively.Conclusion：The prevalence of DM may associate with the risk of colorectal cancer.

关 键 词：糖尿病 结直肠癌 生态学研究 

分 类 号：R587.1[医药卫生—内分泌]