蒙古族高血压患者血浆中神经降压素和神经肽Y的测定  

Plasma neurotensin and neuropeptide Y levels in patients with essential hypertension of Mongolian nationality

作　　者：佟长青[1] 张雪峰[1] 石淑慧[2] 王久亮[2] 张引国 

机构地区：[1]武警医学院生理学教研室,天津300162 [2]内蒙古医学院第一附属医院

出　　处：《武警医学》1999年第10期559-561,共3页Medical Journal of the Chinese People's Armed Police Force

摘　　要：目的　测定生活在牧区蒙古族原发性高血压患者血浆中的NT和NPY ;探讨在蒙古族原发性高血压发病中的作用。方法　采用放射免疫法。结果　 ( 1)汉族原发性高血压患者血浆NT和NPY的浓度与对照组没有统计学差异 ;( 2 )蒙古族原发性高血压患者血浆NPY的浓度比汉族高血压组和对照组高 (P <0 0 5 ) ,但NT的差别不显著。结论　蒙古族原发性高血压的形成和发展机制可能不同于汉族原发性高血压患者 ,血浆中NPY的浓度增加可能是蒙古族高血压患病率较高的原因之一。Objective Neurotensin (NT) and neuropeptide Y (NPY) levels in blood plasma of Mongolian patients with essential hypertension in pastoral area were determined to study the action of NT and NPY in the essential hypertension patients of Mongolian nationality. Method Radioimmunoassay.Results (1)The difference in NT and NPY in blood plasma of patients with essential hypertension of Han nationality was not statisticaly significant,compared with the control group;(2)NPY levelt in blood plasma of Mongolian hypertensive patients was significanthy higher than those in the control group and the Han nationality hypertensive group(P<0.05), while the differencein plasma NT levels was not statistically significant between the four groups.Conclusion The mechanism of develpment essential hypertension in the Mongolians of may differ from that in the Han people.The increase in blood plasma NPY level may be one of reasons for higher incidence of essential hypertension in the Mongolian population.

关 键 词：蒙古族 高血压 神经降压素 神经肽Y 

分 类 号：R544.102[医药卫生—心血管疾病]