爱灵生乐(2036)螺旋藻双歧胶囊对抗生素相关性腹泻小鼠的治疗作用  

Therapeutic effect of Ai Ling Sheng Le (2036) spirulina-bifido capsule on antibiotic induced

作　　者：钟志强[1] 左丽[1] 曾敏瑜 

机构地区：[1]贵阳医学院免疫教研室,贵州贵阳550004 [2]广州市荔湾区中医医院,广东广州510104

出　　处：《中国微生态学杂志》2011年第4期323-324,327,共3页Chinese Journal of Microecology

摘　　要：目的采用盐酸林克霉素诱发小鼠相关性腹泻模型,观察螺旋藻、婴儿型双歧杆菌及其混合物爱灵生乐(2036)螺旋藻双歧胶囊(胶囊内容物,含婴儿型双歧杆菌、螺旋藻,下同)对抗生素相关性腹泻小鼠的治疗作用。方法经口投予盐酸林克霉素0.15 g/(d.鼠),连续3 d,然后经口分别给予螺旋藻、双歧杆菌及爱灵生乐(2036)螺旋藻双歧胶囊1.66 g/(kg.b.w),连续5 d。结果经口投予螺旋藻、婴儿型双歧杆菌及爱灵生乐(2036)螺旋藻双歧胶囊1.66 g/(kg.b.w),连续5 d,能有效改善盐酸林克霉素诱发的小鼠相关性腹泻症状,特别是给予爱灵生乐(2036)螺旋藻双歧胶囊组,可有效治疗盐酸林克霉素诱发小鼠相关性腹泻。结论螺旋藻与双歧杆菌复合制剂对抗生素相关性腹泻有明确治疗作用。Objective To evaluate the effect of spirulina and Bifidobacterium infantis on antibiotic（lincomuycin） induced diarrhea.Method Oral administration of lincomycin 0.15 g/（day·mouse） was given continuously for 3 days.Then each group of mice was fed respectively with spirulina,Bifidobacterium infantis,and a mixture of spirulina and Bifidobacterium infantis 1.66 g/（kg·b·w） for 5 consecutive days.Result Oral administration of spirulina Bifidobacterium infantis and Ai Ling Sheng Le improved the symptoms of antibiotic induced diarrhea effectly,especially Ai Ling Sheng Le.Conclusion The mixture of spirulina and Bifidobacterium infantis is more effective than spirulina and Bifidobacterium infantis alone in relieving diarrhea induced by lincomycin.

关 键 词：螺旋藻 双歧杆菌 抗生素相关性腹泻 

分 类 号：R378.992[医药卫生—病原生物学]