中药制剂预防恶性肿瘤化疗毒副作用的临床观察与分析  

Clinical observation and analysis of the side effects of preventing malignant tumor and chemotherapy in TCM

作　　者：庞香茹 

机构地区：[1]河南省西峡县人民医院,河南西峡474500

出　　处：《中医临床研究》2011年第7期51-52,共2页Clinical Journal Of Chinese Medicine

摘　　要：目的:观察分析中药制剂预防恶性肿瘤化疗时白细胞减少的临床效果。方法:两组基本化疗方案相同。观察组给予参麦针40ml,黄芪针40ml,对照组给予鲨肝醇、利血生及维生素B4等,化疗开始后7天和14天,分别检测外周血白细胞计数、肝功能,并统计分析。结果:观察组130例:显效103,有效19例,无效8例,总有效率93.84%(122/130)。对照组130例,显效30例,有效56例,无效44例,总有效率66.15%(86/130)。两组总有效率统计学处理差异有显著性(P<0.01)。结论:参麦和黄芪针具有气血双补之功效,能使骨髓造血系统活性增强,有效防治恶性肿瘤化疗时骨髓抑制的毒副作用。Objective： To observe and analyze the clinical effect of the WBC reduction when preventing malignant tumor and chemotherapy in TCM. Methods： Two groups of the basic chemotherapy programwere the same. The observation group was treated with 40 ml of the Shenmai needle and 40ml of the Huangqi needle. The control group was treated with batilol, leucogen and Vit B4 etc. 7 days and 14 days after the beginning of the chemotherapy, detecting the peripheral WBC, liver function, then counting and analyzing them. Results： Of all the 130 cases in the observation group, 103 cases were markedly, 19 cases were effective, 8 cases were invalid.the total effective rate was 93.84% （122/130）. Of all the 130 cases in the control group, 30 cases were markedly, 56 cases are effective, 44 cases were invalid, the total effective rate was 66.15% （86/130）. There were obvious statistical analysis differences of the total effective rate in the two groups （P〈0.01）. Conclusion： Shenmai and Huangqi needles have the double functions of complementing the gas and the blood which can also strengthening the bone marrow hematopoietic system. Meanwhile, its efficient to prevent the side effects of the bone marrow inhibition when doing malignant tumor chemotherapy.

关 键 词：参麦针 黄芪针 恶性肿瘤化疗 毒副作用防治 

分 类 号：R273[医药卫生—中西医结合]