热习服干预对海训官兵胃肠激素和免疫状况的影响  

Effects of heat acclimatization on gastrointestinal hormone and cellular immune function of the marine training personnel

作　　者：陈剑伟[1] 黄文[1] 鞠金涛[1] 钟海忠[1] 徐纪平[1] 

机构地区：[1]第二军医大学长海医院野战内科研究所,上海200000

出　　处：《中国热带医学》2011年第2期195-197,共3页China Tropical Medicine

基　　金：全军"十一五"医药卫生科技重点基金(06Z026);全军"十一五"医药卫生科研攻关基金(06G057)

摘　　要：目的探讨热习服干预对海训官兵血浆胃肠激素和免疫状况的影响。方法 125名在东南沿海某地进行夏季海训官兵随机分为热习服干预组和对照组。在海训前对热习服组60名官兵进行人工热间和室外着雨衣热习服干预12d,随后两组官兵均执行为期2个月的海训任务;放射免疫法检测海训前后血浆胃动素(MTL)、血管活性肠肽(VIP)和生长抑素(SS)水平,流式细胞仪检测海训前后外周血T、B、NK淋巴细胞亚群的变化。结果热习服干预组官兵海训前后血浆MTL、VIP和SS水平差异无统计学意义(P>0.05),而对照组官兵海训后血清MTL较海训前明显增高,VIP和SS水平显著降低(P<0.05);海训后热习服干预组官兵CD3+、CD3+CD4+、淋巴细胞和CD4+/CD8+均明显高于对照组(P<0.05),CD3+CD8+和CD3-CD56+均明显低于对照组(P<0.05)。结论适当热习服干预能提高海训官兵胃肠功能稳定性和细胞免疫功能。Aim To observe the effects of heat acclimatization on gastrointestinal hormone and cellular immune function of the marine training personnel.Methods There 125 marine training personnel in southeast area in Summer were randomly divided into 2 groups：the heat acclimatization group（60） and the control group（65）.The levels of plasma motilin（MTL）,vasoactive intestinal peptide（VIP） and somatostatin（SS） of the personnel in the two groups determined by radioimmunoassay two months before and after marine training.The percentage of T,B and NK cell subpopulation were assessed by flow cytomtry.Results There was not significant difference in levels of MTL,VIP and SS before and after marine training（P0.05）.While the level of MTL in the control group was significantly increased and the levels of VIP and SS were significantly decreased after marine training as compared to that before training（P0.05）.Compared with control group,the levels of CD3＋,CD3＋CD4＋,CD4＋/CD8＋ in the heat acclimatization group increased significantly（P0.05） and that of CD3＋CD8＋,CD3-CD56＋ decreased significantly（P0.05）.Conclusion Suitable heat acclimatization can enhance function of gastrointestinal system and cellular immune in the marine training personnel.

关 键 词：热习服 海训 胃肠激素 细胞免疫 

分 类 号：R392.1[医药卫生—免疫学]