纤维支气管镜检查对结节病诊断的临床价值  

Diagnosis value of fiberoptic bronchoscopy in sarcoidosis

作　　者：张嵩[1] 马卫霞[1] 姜淑娟[1] 李元堂[2] 王永康[3] 

机构地区：[1]山东大学附属省立医院呼吸内科,济南250021 [2]山东大学附属省立医院细胞室,济南250021 [3]山东大学附属省立医院病理科,济南250021

出　　处：《国际呼吸杂志》2011年第8期605-608,共4页International Journal of Respiration

基　　金：山东省科技发展计划项目（2009GG10002061）

摘　　要：目的评价经纤维支气管镜下不同取材对结节病诊断的价值。方法回顾性分析50例经纤维支气管镜检查，采用肺内活检（包括经支气管黏膜活检和经纤维支气管镜肺活检）、经气管镜针吸活检（TBNA）和经气管镜超声引导针吸活检术（EBUS-TBNA）等方法获取标本，经病理学或细胞学检查确诊为结节病的患者，比较不同取材及联合取材检测结节病的阳性率。结果经EBUS-TBNA和TBNA诊断为结节病的患者的阳性率分别为86．7％和82．5％，与肺内活检检查的阳性率（66．7％）相比，差异显著。结论纤维支气管镜检查是确诊结节病的重要手段之一，EBUS—TBNA和TBNA检查创伤性小，安全性好，准确率高，在结节病的诊断中有较高的应用价值。Objective To investigate the diagnosis value of fiberoptic bronchoscopy in sarcoidosis. Methods 50 patients with sarcoidosis were retrospectively analyzed and the positive rate of sarcoidosis was compared among transbronchial biopsy or transbronchial lung biopsy, transbronchial needle aspiration （TBNA） and endobronchial ultrasound-guided transbronchial needle aspiration （EBUS TBNA）. Results The positive rate of sarcoidosis confirmed by EBUS TBNA and TBNA was 86.7 % and 82.5 %, and the positive rate of sarcoidosis confirmed by lung biopsy was 66.7%. Conclusions Fiberoptic bronchoscopy is an important means in the diagnosis of sarcoidosis. EBUS-TBNA and TBNA are safe and accurate. They have a higher value in the diagnosis of sarcoidosis.

关 键 词：经气管镜超声引导针吸活检术 结节病 纤维支气管镜 

分 类 号：R563[医药卫生—呼吸系统]