铜绿假单胞菌密度感应系统调控的毒力因子的致病作用  

Pathogenicity of quorum-sensing system-controlled virulence factors of Pseudomonas aeruginosa

作　　者：简丽娟[1] 陈一强[1] 温红侠[1] 

机构地区：[1]广西医科大学第一附属医院呼吸疾病研究所,南宁530021

出　　处：《国际呼吸杂志》2011年第8期612-615,共4页International Journal of Respiration

摘　　要：铜绿假单胞菌可以产生多种毒力因子，是引起细菌慢性持续感染的重要原因之一。其密度感应系统与其毒力因子的合成密切相关。近年，有大量研究发现其分泌的毒力因子可以影响宿主的免疫系统，产生致病作用。因此，现在就毒力因子的致病作用的相关研究作一综述。Pseudomonas aeruginosa can produce a variety of virulence factors, which is one of the important reasons of chronic persistent bacteria infection. The quorum-sensing system of Pseudomonas aeruginosa is closely related to synthesis of virulence factors. In recent years, numerous studies have found that the virulence factors secreted can influence the host immune system, result in pathogenicity. So this review focuses on the related researches about pathogenicity of virulence factors.

关 键 词：铜绿假单胞菌 密度感应系统 毒力因子 

分 类 号：R515[医药卫生—内科学]