自体肝脏移植治疗晚期泡型肝包虫病  

Treatment of late stage hepatic alveolar echinococcosis by liver autotransplantation

作　　者：王海[1] 景鸿恩[1] 徐小青[1] 戴勇[1] 刘巧玉[1] 王学浩[1] 

机构地区：[1]南京医科大学第一附属医院普外科,210029

出　　处：《腹部外科》2011年第2期99-100,共2页Journal of Abdominal Surgery

摘　　要：目的探讨自体肝脏移植（liver autotransplantation，LA）治疗部分泡型肝包虫病的可行性及围手术期并发症的处理。方法回顾分析2008年1月至2010年1月间6例行LA治疗泡型肝包虫病的病例资料。结果全组除1例术后因门静脉血栓形成并发多脏器功能衰竭死亡外，余者均取得良好疗效。术后发生出血1例，胆漏1例，小肝综合征1例。存活的5例术后均随访10个月，期间生活正常。结论LA为难以切除或切除困难的肝包虫病病变开辟了新的技术路径。如能术中正确处理和加强预防并发症的发生，LA是部分晚期肝包虫病病人最有效的治疗方法，但远期疗效尚在随访中。Objective To explore the curative feasibility of hepatic alveolar echinococcosis （HAE） by liver autotransplantation（LA）and the management of perioperative complications. Methods The clinical data of 6 cases of HAE receiving LA during Jan. 2008 to Jan. 2010 were retrospectively studied. Results In 6 cases,5 cases obtained satisfactory curative effectiveness except 1 death of mul tiple organ failure caused by portal vein thrombosis. Main complications included postoperative bleed- ing, bile leak and small for-size syndrome,etc. Conclusion LA creates a new way to cure those whose HAE-occupying lesions are impossible or difficult to be reseeted. LA is the most effective method to cure intractable HAE if correct handling in operation and prevention of perioperative complication were performed. The long-term outcomes are still in the follow-up.

关 键 词：移植 自体 棘球蚴病 肝 围手术期医护 

分 类 号：R532.320.5[医药卫生—内科学]