BiPAP呼吸机治疗AECOPD合并Ⅱ型呼吸衰竭的价值  

Investigation of the value of BiPAP in treating patients of AECOPD with type Ⅱ respiratory failure

作　　者：邓思健[1] 伍晓锋[1] 伍惠红[1] 袁桂影[1] 钟海波[1] 

机构地区：[1]广州市红十字会医院暨南大学第四附属医院呼吸内科,广东广州510220

出　　处：《广州医学院学报》2010年第4期26-28,共3页Academic Journal of Guangzhou Medical College

摘　　要：目的：探讨BiPAP呼吸机在治疗慢性阻塞性肺疾病急性加重期（AECOPD）合并Ⅱ型呼吸衰竭中的临床应用价值.方法：回顾性分析本院呼吸内科2008年5月-2009年9月48例AECOPD合并Ⅱ型呼吸衰竭实施BiPAP呼吸机经口鼻面罩正压通气治疗患者的临床资料（治疗组）,并与科室同时期52例AECOPD合并Ⅱ型呼吸衰竭未实施机械通气治疗患者（对照组）的临床资料进行比较分析,2组患者在年龄、性别、病程及入院时的血气分析各指标方面均差异无统计学意义（P＞0.05）.对照组给予抗感染、祛痰、平喘等常规治疗,辅以持续低流量鼻导管吸氧 治疗组在常规治疗的基础上,给予BiPAP呼吸机辅助呼吸,每天达12 h以上.治疗前,治疗48 h及1 W后分别查血气分析,观察pH、PaCO2、PaO2、SaO2的变化,记录住院天数,住院费用.结果：治疗组与对照组相比,治疗组血气分析改善明显,临床症状缓解快,住院天数明显缩短.两组相比差异有统计学意义（P＜0.05）.结论：AECOPD合并Ⅱ型呼衰的患者,采用BiPAP呼吸机辅助呼吸,可明显改善机体缺氧及酸中毒,临床症状缓解快,并且能明显缩短患者的住院天数,减轻患者的经济负担.Objective：To investigate the clinical application value of the bilevel positive airway pressure （BiPAP） in patients with acute exacerbations of chronic obstructive pulmonary disease （AECOPD） combined with type Ⅱ respiratory failure. Methods ：48patients of AECOPD with type Ⅱ respiratory failure were treatment group, compare with 52 patients of AECOPD with type Ⅱ respiratory failure were control group, during the period from May 2008 to September 2009. There are not significant difference in patients＇ age, gender, symptom and original arterial gas analysis between two groups. The control group received the routine therapy including anti - infection, eliminating phlegm, wheeze remission assistant with low-flow oxygen therapy by endonasal catheter continually; and the treatment group received BiPAP breathing machine assisted ventilation holding on at least 12 hours and the routine therapy. The measures of arterial gas analysis,including pH, PaCO2 , PaO2 and SaO2 were observed before and after therapy 48 hours and 1 week, meanwhile, the hospital days and expense were counted. Results： Compared with control group, arterial gas analysis was significantly improved in treatment group. The clinical symptoms relieved rapidly, and the hospital days reduced in treatment group. There was significant difference between the two groups （ P 〈 0.05 ）. Conclusion ： The organism hypoxia and acidosis are significantly improved in the patients of AECOPD with type Ⅱ respiratory failure who are treated with BiPAP assisted ventilation, the clinical symptoms are alleviated, the hospital days and the financial burden of the patients are alleviated.

关 键 词：慢性阻塞性肺疾病 Ⅱ型呼吸衰竭 BIPAP呼吸机 

分 类 号：R197.39[医药卫生—卫生事业管理]