姜黄素的提取分离与药理作用研究进展  

Advances in studies on extraction,separation,and pharmacological action of curcumin

作　　者：罗廷顺[1] 李洪文[1] 刘正文[1] 刘光明[1] 

机构地区：[1]大理学院药学院,云南大理671000

出　　处：《现代药物与临床》2011年第2期102-107,共6页Drugs & Clinic

摘　　要：姜黄素是姜黄属植物中的主要活性成分,具有抗癌、抗氧化、抗炎、清除自由基、抗微生物以及对心血管系统、消化系统等多方面药理作用,有较好的临床应用价值和研发潜力。随着提取分离技术的发展,目前有多种方法从植物中提取精制姜黄素。对近年来研究姜黄素的酶法、超临界CO2萃取法等提取方法,聚酰胺吸附、大孔树脂吸附等分离方法及其在保护心脑血管和抗肿瘤等方面的药理作用进行综述,为进一步开发利用姜黄素提供依据。Curcumin is one of the major active ingredients in plants of Curcuma L. and has many pharmacological effects, such as anti-cancer, anti-oxidant, anti-inflammatory, free radical scavenging, and anti-microbial effect in the cardiovascular system and digestive system, and so on. It has better clinical application and developping potential of new drug. With the development of extraction and isolation technology, there are many ways to extract refined curcumin from plants. The recent studies of cureumin extraction methods, i.e. enzyme method and supercritical CO2, separation methods, i.e. polyamide adsorption, maeroporous resin adsorption, pharmacological effects of proventing cardio-cerebro-vascular and anti-tumor are reviewed to provide the basis evidence for further utilization of curcumin.

关 键 词：姜黄素 提取 分离 保护心脑血管:抗肿瘤 

分 类 号：R965.2[医药卫生—药理学]