紫杉醇微孔载药支架在非ST段抬高急性冠脉综合征介入治疗中的应用研究  

Study on application of Yinyi TM paclitaxel-eluting stent in the treatment for non ST elevation acute coronary syndrome

作　　者：谢勉[1,2] 党群[2] 

机构地区：[1]天津中医院大学,天津300073 [2]天津市南开医院,天津300100

出　　处：《现代中西医结合杂志》2011年第13期1566-1568,共3页Modern Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的评价垠艺TM紫杉醇微孔载药支架在非ST段抬高急性冠脉综合征介入治疗中的安全性和有效性。方法将97例非ST段抬高急性冠脉综合征患者随机分为实验组47例和对照组50例,分别置入垠艺TM紫杉醇药物涂层支架60枚和Partner支架72枚。随访术后6个月2组不良心脏事件(MACE)发生率,术后30 d MACE及术后6个月再狭窄率。结果 2组随访6个月,均无心源性死亡、非致死性心肌梗死。实验组8例、对照组3例冠脉造影复查时发现支架内再狭窄,予行支架内球囊扩张术治疗,手术成功。结论置入垠艺TM紫杉醇药物涂层支架术后6个月,冠脉再狭窄率和MACE发生率与置入Partner者相似,这一结论仍有待大规模、多中心的随机对照试验进一步证实。Objective It is to evaluate the safety and efficacy of Yin YiTM paclitaxel-eluting stent in the interventional therapy for non ST elevation acute coronary syndrome.Methods 97 patients with non ST elevation acute coronary syndrome were randomly divided into two groups： 47 cases in experimental group and 50 cases in control group,and they were implanted 60 Yin YiTM paclitaxel-eluting stents and 72 Partner stents respectively.MACE after 6 months and after 30 days,ISR after 6 months were in both groups followed up after operation.Results There was no cardiogenic death case and non-fetal myocardial infarction case during six months＇ following up in both group.8 cases with stent restenosis in experimental group and 3 cases in control group were found by coronary arteriongraphy,and they were treated with stent balloon dilatation.All the operations were successful.Conclusion In 6 months after Yin YiTM paclitaxel-eluting stent implanting,coronary artery restenosis rate and MACE occurrence rate is similar to Partner stent.This conclusion still need to be further confirmed by large-scale,multi-center,randomized controlled trials.

关 键 词：垠艺TM紫杉醇微孔载药支架 经皮冠状动脉介入治疗 Partner雷帕霉素支架 

分 类 号：R541.4[医药卫生—心血管疾病]