肾源性系统性纤维化与磁共振含钆对比剂关系研究  

Research on Correlation of Nephrogenic Systemic Fibrosis with Exposure to Gadolinium Contrast Agents

作　　者：温生宝[1] 李文方[1] 

机构地区：[1]青海大学附属医院影像中心,青海西宁810001

出　　处：《现代诊断与治疗》2011年第2期80-82,共3页Modern Diagnosis and Treatment

摘　　要：肾源性系统性纤维化(NSF)是一种仅发生于肾功能不全患者的少见但严重的后天性获得性、系统性疾病,以广泛的组织纤维化为特征。其病因尚未明确。最近有报道指出使用含钆造影剂和NSF的发病有较强的相关性。本文就NSF的流行病学、临床病史和病理学特征、含钆造影剂在NSF发病中所扮演的角色,以及放射科医师在这个问题上应该注意的事项做一综述。Nephrogenic systemic fibrosis（NSF） is a kind of rare but serious acquired and systemic disease,which only occurs in patients with renal insufficiency.It is characterized by a wide of tissue fibrosis.NSF＇s etiology is not clear yet.Recent reports have suggested that there is strong correlation between the usage of gadolinium-containing contrast agents and the incidence of NSF.The epidemiology,clinical history and pathological features of NSF,the role of gadolinium-containing contrast agents in the disease as well as some items which radiologists should pay attention to are illustrated.

关 键 词：纤维化 肾疾病 对比剂 钆 

分 类 号：R692[医药卫生—泌尿科学] R445.2[医药卫生—外科学]