心肌缺血预适应在急性心肌梗塞中的临床意义  

Clincal significance of ischemic preconditioning in acute myocardial infarction

作　　者：张素荣[1] 关慧灵[1] 张永春[1] 刘建恩[1] 黄陆力[1] 

机构地区：[1]新乡医学院一附院内二科

出　　处：《新乡医学院学报》1999年第2期127-128,共2页Journal of Xinxiang Medical University

摘　　要：目的探讨心肌缺血预适应在急性心肌梗塞中的临床意义。方法５８例ＡＭＩ患者分为梗塞前２４ｈ内有心绞痛组３５例，梗塞前２４ｈ内无心绞痛组２３例。入院后按统一方案治疗，观察比较两组的心肌酶峰值、严重心律失常发生率及院内死亡率。结果有梗塞前心绞痛组心肌酶峰值、严重心律失常发生率及院内死亡率显著低于无梗塞前心绞痛组（Ｐ＜００５）。结论梗塞前有心绞痛发作能有效的诱导缺血预适应，对心肌起保护作用，使心肌梗塞面积缩小，心律失常发生率及死亡率降低。Objective To estimate the clincal significance of ischemic preconditioning in acute myocardial infarction MethodsFifty-eight of AMI patients were divided into tow groups according to the occurrance of angina pectoris(AP) 24 hours before AMI, one group are 35 cases who has AP,the other group in 23 cases without APBoth goup were treated with the same methods and the peak values of myocardial enzyme,the incidence of severe arrhythemia and mortality of hospital were observed Results The peak values of myocardial enzyme,the incidence of severe arrhythemia and mortality of hospital in group 1 is very lower than that of group ConclusionThe patiets with occurance of angina pectoris before infarction by precondioning can result and reduce the size of infarction,incidence of arrythmia and mortality

关 键 词：缺血预适应 急性 心肌梗塞 临床意义 

分 类 号：R542.22[医药卫生—心血管疾病]