低密度脂蛋白胆固醇直接测定与三种间接计算法比较  

COMPARISON BETWEEN THE RESULTS OF LDL-C DETERMINED BY DIRECT TESTING METHOD AND INDIRECT CALCULATION METHODS

作　　者：张军力[1,2] 王广结[1,2] 王育民[1,2] 孟俊 

机构地区：[1]内蒙古医学院第一附属医院检验科 [2]呼和浩特市第一医院检验科

出　　处：《内蒙古医学院学报》1999年第2期108-110,共3页Acta Academiae Medicinae Neimongol

摘　　要：目的：分析比较低密度脂蛋白胆固醇（ＬＤＬ－Ｃ）直接测定与三种间接计算法的适用范围和准确性。方法：对１０６名患者进行ＬＤＬ－Ｃ、总胆固醇（ＴＣ）、甘油三酯（ＴＧ）、高密度脂蛋白胆固醇（ＨＤＬ－Ｃ）测定，采用三种不同的间接计算公式得出ＬＤＬ－Ｃ与直接测定法结果进行比较。结果：只有Ｈａｔａ修改法间接计算与直接测定法结果无显著性差异（Ｐ＞００５），Ｆｒｉｅｄｅｗａｌｄ公式和Ｄｅｌｏｎｇ公式间接法均比直接测定法高，有显著性差异（Ｐ＜００１）。结论：ＬＤＬ－Ｃ间接计算法受到多因素影响，不可靠，直接测定法是一个较好的方法。Objective:To analyze and compare the applying scope and accuracy of the results of LDL-C obtained by direct testing method and indirect calculation methods.Methods:The values of LDL-C,total cholesterol,triglyceride and high density lipoprotein cholesterol(HDL-C)from 106 patients were tested,and the results were conpared with the results obtained by indirect formula methods to get some useful conclusions.Results:Compared with the direct testing method,the unique result determined by Hata modifying method have no notable difference ( P >0.05),the values determined by the other indirect methods of Friedewald formula and Delong formula are higher than the results tested by the direct testing method and the difference is notable( P <001).Conclusion:Using indirect calculation methods,the values of LDL-C are affected by more factors and the results are not reliable.The direct testing method is a better method.

关 键 词：脂蛋白类 胆固醇 方法 比较 

分 类 号：R446.1[医药卫生—诊断学]