聚磷酸钙纤维增强α-磷酸三钙/纳米羟基磷灰石骨水泥复合材料的力学性能  

Mechanical properties of calcium polyphosphate fiber-reinforced alpha-tricalcium phosphate/nano-hydroxyapatite bone cement composites

作　　者：史雪婷[1] 徐立新[1] 石宗利[1] 

机构地区：[1]兰州交通大学机电工程学院材料科学系,甘肃省兰州市730070

出　　处：《中国组织工程研究与临床康复》2010年第51期9535-9538,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

摘　　要：背景:利用纤维增强磷酸钙骨水泥的机制很早就被人们认识和利用。由于非吸收性纤维存在生物相容性低及应力遮挡等问题,近期的研究热点主要是可降解吸收的生物活性纤维对磷酸钙骨水泥性能的影响。目的:制备聚磷酸钙/(α-磷酸三钙/纳米羟基磷灰石)骨水泥复合材料,观察聚磷酸钙对磷酸钙骨水泥力学性能的增强效果。方法:利用固相反应法和湿法反应法分别制得α-磷酸三钙和纳米羟基磷灰石粉末,再将2种粉末按不同比例混合进行高温处理,然后将其与不同质量比、不同长度的聚磷酸钙纤维复合制成骨水泥试样。对试样进行凝固时间、力学性能测试,利用扫描电镜观察试样微观结构。结果与结论:聚磷酸钙长度为3mm、含量为10%时,抗压强度为66.43MPa,抗弯强度为13.86MPa。扫描电镜显示聚磷酸钙在磷酸钙骨水泥基体中分布均匀,结合性能好。在Ringer’s溶液中浸泡3个月,纤维仍具有一定的增强效果。提示聚磷酸钙纤维对α-磷酸三钙/纳米羟基磷灰石骨水泥有一定的增强作用,聚磷酸钙/(α-磷酸三钙/纳米羟基磷灰石)骨水泥复合材料具有良好的力学性能。BACKGROUND：The theory of using fibers as reinforced materials to improve the properties of calcium polyphosphate（CPC） has been known and utilized.Because of low biocompatibility and stress-shielding on non-absorbable fibers,it becomes a hot point to study influence of degradable and absorbable fibers on the properties of CPC.OBJECTIVE：To prepare CPP/alpha-tricalcium phosphate/nano-hydroxyapatite（α-TCP/n-HAP） bone cement composites,and to study the results of CPP fiber to reinforce mechanical properties of CPC bone cement.METHODS：Firstly,α-TCP and n-HAP powder were made using solid reacting and wet reacting methods.Secondly,the two types of powder were mixed as different proportions and treated in high temperature.Thirdly,the mixed powder was compounded with CPP fiber according to different contents and lengths,with which bone cement samples were made out.Finally,hardening time and mechanical properties of the sample were measured,and microstructure of the hardened samples was observed with scanning electron microscope.RESULTS AND CONCLUSION：When the amount of CPP fiber was 10% and its length was 3 mm,the compressive strength was about 66.43 MPa and the bending strength was about 13.86 MPa.Scanning electron microscope showed that CPP fibers were distributed uniformly in CPP bone cement and combined well with the base.After immersing in Ringer＇s fluid for three months,the CPP fibers still had certain results of reinforcing strength.The CPP fiber can increase strength of CPP/α-TCP/n-HAP bone cement composites,which have good mechanical properties.

关 键 词：聚磷酸钙纤维 骨水泥 复合材料 纤维增强 力学性能 生物材料 

分 类 号：R318[医药卫生—生物医学工程]