椎动脉起始部支架置入术后再狭窄的病因及防治  

Causes and prevention of in-stent restenosis of vertebral artery origin after stenting

作　　者：赵慧玭[1,2] 李慎茂[1] 张广平[1] 

机构地区：[1]首都医科大学宣武医院介入中心,北京100053 [2]北京市普仁医院

出　　处：《介入放射学杂志》2010年第12期1000-1003,共4页Journal of Interventional Radiology

摘　　要：椎动脉狭窄是后循环梗死的重要病因,尤以起始部的狭窄更为常见。介入治疗已成为治疗椎动脉狭窄的重要方法。但是不得不面对椎动脉起始部支架置入术后再狭窄率较高的问题。近年来,随着关于再狭窄的病理生理学基础研究的深入,相关的防治方法不断发展。口服药物治疗、各种涂层支架、放射性血管支架与磁化支架等为解决支架置入术后再狭窄提供了各种方法。本文就其病因及防治作一综述。Vertebral artery stenosis is an important cause of posterior circulation stroke.Vertebral artery stenosis most commonly occurs at its origin site.In recent years,balloon angioplasty and stent implantation have been widely empolyed in the treatment of vertebral artery origin stenosis.However,the long term outcome of stent implantation is affected by in-stent restenosis.Multiple contributory factors have been identified,but clear understanding of the overall underlying mechanism remains an enigma.With the development of pathophysiology,prevention and treatment methods of in-stent restenosis have been improved.In recent years,drug-eluting stents,radioactive stents and magnetic stents have been widely applied.To some extent,these stents and drug therapy can solve the problem of restenosis.This article aims to review the clinical application and the up-to-date research progresses in preventing and managing vertebral artery origin restenosis.

关 键 词：椎动脉起始部 支架 再狭窄 

分 类 号：R543.4[医药卫生—心血管疾病]