电刺激器放置时间对周围神经再生影响的实验研究  

Experimental Study on the Effect of Implanting Time of Current Stimulator to Peripheral Nerve Regeneration

作　　者：于占革[1,2,3] 贾继峰[1,2,3] 于维良[1,2,3] 赵承滨[1,2,3] 邢燕[1,2,3] 张中彦[1,2,3] 杨轶胜 

机构地区：[1]哈尔滨医科大学第一临床医学院骨科 [2]巴彦县人民医院骨科 [3]庆安县人民医院骨科

出　　处：《中国矫形外科杂志》1999年第7期517-519,共3页Orthopedic Journal of China

摘　　要：目的：探索周围神经再生开始后，挪开电刺激器是否对神经再生有影响。方法：把Ｗｉｓｔａｒ鼠制成坐骨神经离断模型。Ａ、Ｂ组为电刺激器放置组；Ｃ组将医用硅胶管套在神经缝合处。Ａ、Ｃ组持续观察４周；Ｂ组２周时取出电刺激器，继续观察２周。结果：Ａ、Ｂ组在形态学、电生理学指标上均优于Ｃ组，Ａ、Ｂ组间差异无显著意义。结论：电刺激器对周围神经再生有促进作用，一旦神经再生开始去除电场对神经再生不产生影响。Objective:To study when peripheral nerve regeneration has begun whether there was any influence on the nerve regeneration after removing of the current stimulator.Methods:Wistar rats weight 200250g were selected,sciatic nerve transected models were made,which were divided into A,B,C three groups.Group A and group B current stimulators were implanted,group C silicone tubes were placed in the anastomotic site.Group A and group C were observed for 4 weeks.Group B current stimulators were removed at 2 weeks postoperatively and observed another 2 weeks.Results:The electrophysiological and morphometric index in the experimental group were much better than those in the control group, and there was no significant difference between group A and group B.Conclusion:current stimulator could facilitate peripheral nerve regeneration,once the regeneration has commenced, the removal of the electric field had no effect on regeneration.

关 键 词：电刺激器 周围神经再生 神经再生 实验 放置时间 

分 类 号：R651.3[医药卫生—外科学]