来曲唑和克罗米酚对排卵障碍者的促排卵效果的比较研究  

A Comparison of the Effects of Letrozole Versus Clomiplhene Citrate for Ovulation Induction in Patients with Ovulatory Dysfuction

作　　者：林春莲 

机构地区：[1]钦州市妇幼保健院生殖中心,广西钦州535000

出　　处：《中外医疗》2011年第8期103-104,共2页China & Foreign Medical Treatment

摘　　要：目的探讨来曲唑在人工授精促排卵中的治疗效果。方法选择人工授精促排卵治疗患者80例,随机分为A组(40例):口服来曲唑(LE),B组(40例):口服氯米酚(CC),通过观察2组子宫内膜厚度、成熟卵泡的个数、妊娠率和流产率比较用药效果。结果 2组成熟卵泡个数、流产率无明显差异(P>0.05);子宫内膜厚度、妊娠率有明显差异(P<0.05)。结论对因女性排卵障碍引起的不孕,用LE促排卵,可以减少CC抗雌激素样作用对子宫内膜的不良影响,使子宫内膜有较好的容受性,有利于妊娠,值得推广应用。Objective To explore the effect of the letrozole in ovulation induction.Methods 80 cases of patients with infertile were divided into two groups.Group A（40 cases）took letrozole（LE）.Group B（40 cases）took clomiphere citrate（CC）.The endometrial thickness,number of follicles,pregnancy rates,miscarriag rates were measured.Results Endometrial thickness,pregnancy rates in group A was significantly higher than that in group B.The number of follicles and miscarriag rates of both groups were not significantly different.Conclusion LE can reduce the effect about CC anti-estrogen,improve the endometrical acceptable and pregnancy rates.

关 键 词：来曲唑 人工授精 氯米酚 促排卵 

分 类 号：R711.7[医药卫生—妇产科学]