福尔利联合舒芬太尼对腹腔镜全麻苏醒期躁动的影响  

Etomidate Fat Emulsion Injection and Propofol with Sufentanil Inhibit Recovery Restlessness after General Anesthesia In Patients Undergoing Gynecological Laparoscopic Surgery

作　　者：汪国香[1] 黄丽霞[1] 范皓[1] 陶凡[1] 

机构地区：[1]杭州市红十字会医院麻醉科,杭州310003

出　　处：《浙江中西医结合杂志》2011年第4期222-224,共3页Zhejiang Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的:观察术后应用福尔利和丙泊酚联合舒芬太尼抑制全麻苏醒期躁动的疗效。方法:选择ASA-I或Ⅱ级全麻下行妇科腹腔镜手术且术毕出现苏醒期躁动患者46例,随机分为I、Ⅱ两组,每组23例。当患者出现四肢乱动、烦躁不安、答非所问时I,组静注福尔利0.15mg/kg,Ⅱ组静注丙泊酚1.0mg/kg。两组患者均静脉注射舒芬太尼0.15μg/kg。观察和比较两组抗躁动起效时间和清醒时间、两组患者的Ramsay评分及副作用(恶心、呕吐、肌颤、循环呼吸抑制等)。结果:I、Ⅱ两组镇静深度均在4分以上,均能有效抑制躁动;Ⅱ组比I组起效快,但差异无统计学意义(P>0.05),两组清醒时间比较差异亦无统计学意义(P>0.05)I;组有2例、Ⅱ组9例发生循环呼吸抑制,差异有统计学意义(P<0.05);两组患者均未发生恶心呕吐和肌颤。结论:福尔利和丙泊酚联合舒芬太尼均能有效抑制全麻苏醒期躁动,福尔利对循环系统影响小,更安全。Objective： To observe the effect of etomidate fat emulsion injection（forry） and propofol with sufentanil inhibiting the restlessness after general anesthesia in patients undergoing gynecological laparoscopic surgery.Methods： Forty-six patients were randomly divided into 2 groups： group I（n=23） and group II（n=23）.Group Ⅰ received forry 0.15 mg/kg and group Ⅱreceived propofol 1.0 mg/kg when patients displayed restlessness.Both groups received sufentanil 0.15 μg/kg.The time of the medicine to produce a marked effect（T1） and patient analepsia（T2）,the level of restlessness,and the incidence of side effects were recorded.Results： No significant difference in T1,T2 and the level of restlessness was noted between the 2 groups（P0.05）.The incidence of respiration and circulation inhibition was significantly lower in group I compared to that in group II（P0.05）.No other side effects were found in both groups.Conclusion： Etomidate fat emulsion injection with sufentanil can effectively inhibit recovery restlessness after general anesthesia with few side reactions.

关 键 词：福尔利 丙泊酚 舒芬太尼 全麻苏醒期 躁动 

分 类 号：R614[医药卫生—麻醉学]