肺结核合并真菌感染或定植的148例临床及耐药分析  

Clinical Feature and Drug Resistance Analysis on Fungi Infected or Colonized in 148 Cases with Pulmonary Tuberculosis

作　　者：杨丽梅[1] 蔡红[1] 班武娟[1] 宋长兴[1] 

机构地区：[1]首都医科大学附属北京胸科医院检验科,北京101149

出　　处：《结核病与胸部肿瘤》2011年第1期48-50,共3页Tuberculosis and Thoracic Tumor

摘　　要：目的探讨肺结核合并真菌感染或定植的临床特点。方法回顾近一年半来我院住院的肺结核合并肺部真菌感染或定植的资料并进行分析。结果合并真菌感染或定植的肺结核主要特点为以老年患者（33．2％），低蛋白血症患者（75．67％）、糖尿病患者（21．62％）、合并肺部细菌感染（40．54％）以及慢性纤维空洞型肺结核患者为主（8．00％）。病原菌以白色念珠菌为主，占75．67％。结论肺结核合并肺部真菌感染或定植的患者有增多趋势，应重视真菌的变迁及耐药菌株的发生。Objective To investigate the clinical features on fungi infected or colonized in patients with pulmonary tuberculosis. Methods We analyzed retrospectively clinical data from inpatients with pulmonary tuberculosis hospitalized in our hospital during one and a half years recently. Results The patients with pulmonary tuberculosis complicated with fungal infection or colonization are mainly the elderly（33.3%）, patients with hypoproteinemia （75.67%）, patients with diabetes mellitus（21.62%）, patients complicated with pulmonary bacterial infection（40.54%） and patients with chronic fibro-cavitative pulmonary tuberculosis （8.00%）. Pathogenic microorganism were mainly Candida albicans. Conclusion The trendency on pulmonary fungal infection or colonization in patients with pulmonary tuberculosis is increasing, fungi strains of variation and drug resistance should be paid more attention.

关 键 词：结核 肺 真菌感染 耐药 

分 类 号：R519[医药卫生—内科学]