甘精胰岛素对2型糖尿病患者生活质量影响的临床研究  

The effects of insulin glargine on quality-of life in patients with type 2 diabetes

作　　者：李艳萍[1] 李红梅[1] 田文真[1] 杜婧[1] 赵茜[1] 

机构地区：[1]宁夏自治区人民医院,宁夏银川750021

出　　处：《宁夏医学杂志》2011年第4期321-323,共3页Ningxia Medical Journal

基　　金：宁夏自治区卫生厅重点课题(2008008)

摘　　要：目的研究甘精胰岛素和预混胰岛素对2型糖尿病患者生活质量和治疗满意度的影响。方法将73例口服药治疗失效的2型糖尿病分成甘精胰岛素+阿卡波糖组和预混胰岛素(NPH)组,分别在治疗前、治疗12、24周时完成糖尿病生活满意度问卷调查。结果两组在12、24周时病人生活质量均较前改善,在治疗依从性和总体满意度方面,甘精胰岛素组比预混胰岛素组有明显改善(P<0.01)。结论甘精胰岛素可改善口服药治疗失效的2型糖尿病患者的生活质量和治疗满意度。Objective To compare quality of life and treatment satisfaction by using insulin glargine and by using NPH insulin in patients with type 2 diabetes.Methods 73 patients with type 2 diabetes were randomly divided into insulin glargine plus oral antididiabetes（OAD） or to NPH insulin（twice daily）,the Diabetes Treatment Satisfaction Questionnaire（DTSQ） were compared at baseline,at weeks 12 and 24 weeks.Results In mean baseline,score were not markedly difference between two groups,and score in treatment satisfaction and flexibility at 12 weeks and 24 weeks was significantly improved with glargine compared with that for NPH（P（0.05））.Conclusion Insulin glargine impruves treatment satisfaction,and improves QoL in comparison with NPH insulin in type 2 diabetes.

关 键 词：糖尿病 胰岛素 生活质量 

分 类 号：R587.1[医药卫生—内分泌]