长春市汽车产业开发区妊娠期糖尿病的流行病学调查  

Epidemiological investigation on gestational diabetes mellitus in development area of automobile industry in Changchun

作　　者：王丽萍[1] 李杰[1] 王晓梅[1] 单秀娟[1] 李晓波[1] 寇长贵[2] 刘雅文[2] 

机构地区：[1]吉林大学第四医院一汽总医院妇产科,吉林长春130011 [2]吉林大学流行病教研室

出　　处：《中国妇幼保健》2011年第12期1846-1849,共4页Maternal and Child Health Care of China

基　　金：吉林省科学技术厅项目〔2008247-01〕

摘　　要：目的:调查长春市汽车产业开发区妊娠期糖尿病的发病情况,分析导致妊娠期糖尿病的相关危险因素,为临床早期识别、诊断和干预提供理论依据。方法:收集接受产前检查的857例孕妇的一般情况和临床资料,并于孕24～28周进行糖筛查,对筛查阳性者或具有GDM高危因素者行75g口服葡萄糖耐量试验(OGTT),将调查到的信息录入SPSS 12.0进行分析。结果:①该地区研究期间妊娠期糖筛查异常率为20.37%(174/854),妊娠期糖耐量受损(GIGT)的发病率为1.75%;妊娠期糖尿病(GDM)的发病率为1.28%,总的妊娠期糖尿病的发病率为3.03%;②单因素分析发现,年龄、体重指数(BMI)及糖尿病家族史与GDM相关;多因素Logistic回归分析也证明,糖尿病家族史、年龄、体重指数(BMI)为GDM的高危因素。结论:长春市汽车产业开发区妊娠期糖尿病的发病率与国内报告相当;BMI、糖尿病家族史、年龄为影响GDM的危险因素;加强妊娠期糖尿病筛查,特别要对具有高危因素的妊娠期妇女引起重视,应早期诊断、早期干预,系统化管理能明显改善妊娠结局,提高人口素质。Objective：To investigate the incidence of gestational diabetes mellitus（GDM） in development area of automobile industry in Changchun,analyze the related risk factors of GDM,provide a theoretical basis for early recognition,diagnosis and intervention.Methods：The general conditions and clinical data of 857 pregnant women receiving prenatal examination were collected,glucose screening was carried out at 24~28 gestational weeks,the cases with positive results or high risk factors of GDM received 75g oral glucose tolerance test（OGTT）,all the data investigated were input into SPSS12.0 software and analyzed.Results：The abnormal rate of glucose screening during pregnancy was 20.37%（174/854）,the incidence of gestational impaired glucose tolerance（GIGT） was 1.75%;the incidence of GDM was 1.28%,the total incidence of GDM was 3.03%.Single factor analysis showed that age,body mass index（BMI） and the history of GDM were related to GDM;multifactor logistic analysis also showed that the history of GDM,age and BMI were the high risk factors of GDM.Conclusion：The prevalence rate of GDM in development area of automobile industry in Changchun is similar to the data reported in other areas in China;BMI,the history of GDM and age are the high risk effect factors of GDM;the screening of GDM should be enhanced,the women with high risk factors of GDM should be paid more attention to;early diagnosis,early intervention and systematical management may improve the pregnancy outcomes and the quality of birth population obviously.

关 键 词：妊娠期糖尿病 发病率 危险因素 

分 类 号：R714.256[医药卫生—妇产科学]