Genetically targeting new neurons in the adult hippocampus  

作　　者：Zhengang Yang Guo-Li Ming Hongjun Song 

机构地区：[1]Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai 200032, China [2]Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA [3]Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA [4]Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA

出　　处：《Cell Research》2011年第2期220-222,共3页细胞研究（英文版）

摘　　要：Neurogenesis, the birth of new neurons from neural stem cells, is known to occur throughout life in two specific regions of the adult mammalian brain, the subgranular zone/hippocampal dentate gyrus and the subventricular zone/olfactory bulb . Adult neurogenesis is a multi-step process （Figure 1）, which includes proliferation and fate specification of adult neural stem cells, morphogenesis, migration, axonal and dendritic development, survival,

关 键 词：海马神经元 成年大鼠 基因定位 神经干细胞 成年哺乳动物 神经发生 海马齿状回 脑室下区 

分 类 号：Q426[生物学—神经生物学] Q421[生物学—生理学]