热敏点灸治疗原发性骨质疏松症及对患者BMD、S-AKP、U-Ca/Cr的影响  

Effect of heat-sensitive point moxibustion on BMD,S-AKP,U-Ca/Cr in patients with primary osteo-porosis

作　　者：李丰[1] 何忠锅[1] 涂国卿[1] 孟羽[1] 曹耀兴[1] 黄小平[1] 

机构地区：[1]江西中医药高等专科学校,抚州344000

出　　处：《中国针灸》2011年第3期223-226,共4页Chinese Acupuncture & Moxibustion

基　　金：江西省卫生厅课题项目:2007A131

摘　　要：目的:比较热敏点灸与口服盖天力治疗原发性骨质疏松症的疗效差异,探讨其相关治疗机制。方法:60例原发性骨质疏松症患者随机分为热敏灸组和盖天力组,每组30例。热敏灸组在足三里、脾俞、肾俞、命门穴上及附近寻找热敏化点,施热敏灸治疗;盖天力组口服盖天力片,每次3片,每天3次。观察两组治疗前后临床疗效及骨密度(BMD)、血碱性磷酸酶(S-AKP)、尿钙/尿肌酐比值(U-Ca/Cr)的变化。结果:热敏灸组总有效率为86.7%(26/30),优于盖天力组的76.7%(23/30)(P<0.05)。治疗后热敏灸组腰椎(L2—L4)骨密度均值较治疗前提高(P<0.05),S-AKP、U-Ca/Cr比值均较治疗前降低(均P<0.05),盖天力组以上指标治疗前后无显著变化(均P>0.05)。结论:热敏点灸治疗原发性骨质疏松症疗效优于口服盖天力片,其机制为抑制骨吸收,增加骨强度,使骨代谢趋于正平衡状态,从而达到增加骨密度、改善临床症状的效果。Objective To compare the curative effects of primary osteoporosis treated with heat-sensitive point moxibustion and Gaitianli （Oyster Shell and Calcium Carbonate Chewable） tablets for oral administration and explore the treatment mechanism. Methods Sixty cases of primary osteoporosis were randomly divided into a heatsensitive point moxibustion group （moxibustion group） and a Gaitianli tablets group （medication group）, 30 cases in each group. In the moxibustion group, the heat sensitized points were searched around Zusanli （ST 36）, Pishu （BL 20）, Shenshu （BL 23） and Mingmen （GV 4） and treated by heat-sensitive point moxibustion; in medication group, Gaitianli tablets were taken by oral administration, 3 pills for once and 3 times a day. The curative effects, bone mineral density （BMD）, alkaline phosphatase （S-AKP） and urinary calcium to creatinine ratio （U-Ca/Cr） in both groups were observed before and after treatment. Results The total effective rate was 86.7% （26/30） in moxibustion group, superior to that of 76.7%（23/30） in medication group （P〈0. 05）. After treatment, the BMD of lumbar vertebrae （L2--L4） mean was improved （P〈0.05）, and the S-AKP and U-Ca/Cr were reduced （all P〈0. 05） ; in medication group, the indexes above were no obvious changes （all P〉0. 05）. Conclusion The therapeutic effect of primary osteoporosis treated with heat-sensitive point moxibustion is superior to that with Gaitianli tablets for oral administration. The mechanism is restraining bone resorption, increasing bone strength, keeping balance of bone metabolism, in order to increase bone mineral density and improve the clinical symptoms.

关 键 词：骨质疏松症 针灸疗法 骨密度 血碱性磷酸酶 尿钙/尿肌酐比值 

分 类 号：R245.8[医药卫生—针灸推拿学]