复方血栓通胶囊和胰激肽酶原治疗NPDR的研究  

Clinical study of the combined application of xueshuantong complex capsule and pancreokinin on nonproliferative diabetic retinopathy

作　　者：林文雄[1] 臧晶[1] 鲍炯琳[1] 周斌兵[1] 朱宇东[1] 李青[1] 

机构地区：[1]广东药学院附属第一医院眼科,中国广东省广州市510080

出　　处：《国际眼科杂志》2011年第4期625-627,共3页International Eye Science

摘　　要：目的:研究探讨复方血栓通胶囊、胰激肽酶原以及两者联合应用在非增殖期糖尿病视网膜病变中的疗效。方法:按照随机、对照的原则,把90例早期糖尿病视网膜病变患者分为3组,第一组服用复方血栓通胶囊;第二组服用胰激肽酶原;第三组同时服用复方血栓通胶囊和胰激肽酶原。疗程为3mo,观察患者治疗前及治疗后的视力、视网膜的变化。对比治疗前后的变化,将观察指标结果量化,利用SAS简明统计软件处理,得出其疗效有无差异性。结果:在本研究中,应用复方血栓通胶囊治疗患者30例60眼,有效43眼,有效率71.6%;应用胰激肽酶原患者30例60眼,有效46眼,有效率76.6%;两者联合应用30例60眼,有效55眼,有效率91.6%。经统计学分析,应用复方血栓通胶囊、胰激肽酶原治疗期非增殖期糖尿病视网膜病变均有效,两组比较无差异性。两者联合应用与单纯应用相比较,统计学分析有差异性。结论:在非增殖期糖尿病视网膜病变的治疗中,复方血栓通胶囊以及胰激肽酶原对其治疗均有效,两者联合应用,疗效更佳。我们得出:中西医结合治疗非增殖期糖尿病视网膜病变是一种疗效较好的方法。AIM：To investigate the effect of xueshuantong complex capsule and pancreokinin on nonproliferative diabetic retinopathy（NPDR）.METHODS：There were 90 patients in our study,randomly divided into xueshuantong complex capsule group,pancreokinin group and combined treatment group.The course of treatment was 12 weeks.Patients’ visual acuity（VA）and ocular fundus were observed before and after drug treatment,the changes were compared.The results of quantitative indicators were dealed with the use of SAS statistical software,any differences in efficacy were analyzed.RESULTS：In this study,xueshuantong complex capsule was applied in the treatment of 30 cases 60 eyes,and effective in 43 eyes with efficiency of 71.6%;pancreokinin in 30 cases 60 eyes,effective in 46 eyes with efficiency of 76.6%;combined treatment in 30 cases 60 eyes,effective in 55 eyes with efficiency of 91.6%.After statistical analysis,application of xueshuantong complex capsule and pancreokinin treatment for NPDR were effective,the two groups showed no differences.Comparison between simple application and joint applications had statistical differences.CONCLUSION：In the early treatment of NPDR,the xueshuantong complex capsule and pancreokinin are valid,their joint applications can offer a better effect.We come to the conclusion that traditional Chinese combined with Western medicine treatment of NPDR is a better way.

关 键 词：非增殖期糖尿病视网膜病变 中西医结合 疗效 

分 类 号：R587.1[医药卫生—内分泌] R774.1[医药卫生—内科学]