调环酸钙安全性初步评价  

Preliminary evaluation on the security of prohexadione-calcium

作　　者：郑先福[1] 赵东生[1] 孙炳剑[1] 郑昊 

机构地区：[1]河南农业大学 [2]郑州郑氏化工产品有限公司,郑州450002

出　　处：《南方农业学报》2011年第3期288-290,共3页Journal of Southern Agriculture

基　　金：河南省重大科技攻关计划项目(102101310600)

摘　　要：【目的】评价调环酸钙原药的急性毒性,为安全使用调环酸钙提供毒理学依据。【方法】按照我国现行《农药登记毒理学试验方法》(GB15670-1995)规定的方法,以SD大鼠为对象,采用一次最大剂量法,对调环酸钙原药进行急性经口、经皮毒性试验。【结果】调环酸钙原药对SD大鼠的急性经口半数致死量(LD50)>5000mg/kg·BW,经皮LD50>2000mg/kg·BW。【结论】调环酸钙对大鼠的急性经口、经皮毒性均属于低毒性,符合绿色农业生产的要求。【Objective】The objective of the present study was to test the acute toxicity of the raw pesticides of prohexadione-calcium, and to provide toxicological basis for using proexhadione calcium safely. 【Method】The tests of acute oral and percutaneous toxicity were undertaken based on the Chinese standards （GB 15670-1995） of Toxicological Test Methods of Pesticides for Registration. 【Result】The acute oral toxicity LD50 of proexhadione calcium on SD rats was over 5000 mg/kg·BW, and the percutaneous toxicity was over 2000 mg/kg·BW. 【Conclusion】The acute oral, percutaneous toxicity of percutaneous toxicity on rats is low, which is safe for human beings and domestic animals.

关 键 词：调环酸钙 植物生长调节剂 急性毒性 安全评价 

分 类 号：S482.81[农业科学—农药学]