动态观察冷沉淀对大量输血患者凝血时间的影响  

Dynamic observation of the influence of cryoprecipitate on the clotting time after massive blood transfusion

作　　者：赫兰辉[1] 邓红艳[1] 曾小奇[1] 秦凡[1] 

机构地区：[1]成都大学附属医院,610081

出　　处：《检验医学与临床》2011年第8期951-951,953,共2页Laboratory Medicine and Clinic

摘　　要：目的观察输注冷沉淀对大量输血后患者出凝血时间的影响与其在临床中的应用价值。方法对3例大量输血后有凝血异常的患者,输注冷沉淀前与输注冷沉淀后24 h内出凝血时间曲线的动态观察并进行统计学分析。结果 3例患者输注冷沉淀前后相比,患者的凝血酶原时间(PT)、凝血酶时间(TT)、部分凝血活酶时间(APTT)均明显缩短,纤维蛋白原(FIB)含量增加。结论冷沉淀的输注对大量输血后并发凝血异常的患者有明显的纠正效果。Objective To observe the influence of cryoprecipitate on the clotting time of patients after massive blood transfusion and its clinical application.Methods Three patients with coagulopathy after massive blood transfusion were dynamic observed and analyzed the curve of clotting time before and in 24 hours infusion of cryoprecipitate.Results The results of three patients were compared before and after infusion of cryoprecipitate,the contents of prothrombin time（PT）,thrombin time（TT）,partial thromboplastin time（APTT）of patients were significantly reduced,and the content of fibrinogen（FIB）was increased after infusion of cryoprecipitate.Conclusion The infusion of cryoprecipitate can improve the situation of patients with coagulopathy after massive blood transfusion effectively.

关 键 词：冷沉淀 大量输血 凝血异常 

分 类 号：R285.5[医药卫生—中药学]