牙周病与2型糖尿病慢性血管并发症的关系  

The Relationship between Periodontal Disease and Chronic Vasculopathy Complications in Type 2 Diabetes

作　　者：付秀立[1] 赵湜[1] 毛红[1] 李竞[2] 

机构地区：[1]华中科技大学同济医学院附属武汉市中心医院内分泌科,430014 [2]武汉大学附属湖北省人民医院

出　　处：《天津医药》2011年第3期224-226,共3页Tianjin Medical Journal

摘　　要：目的:探讨2型糖尿病患者牙周病与慢性血管并发症的关系。方法:将166例2型糖尿病患者按糖尿病并发症分为糖尿病无血管并发症组(A组)、糖尿病微血管并发症组(B组)、糖尿病大血管并发症组(C组)、糖尿病大血管和微血管并发症组(D组),健康者54例作为对照组(E组)。所有研究对象进行口腔检查。检测患者龈炎指数(GI)、临床附着丧失(CAL)均值、牙周袋深度(PD)。结果:(1)糖尿病各亚组PD、GI、CAL值均明显高于正常对照组,差异具有统计学意义(均P<0.05),且B、C、D组高于A组,差异具有统计学意义(P<0.05)。(2)糖尿病患者HbA1c与PD、GI、CAL呈正相关(r分别为0.617、0.593、0.468,均P<0.01)。(3)Logistic回归分析结果显示PD、GI、CAL均是影响糖尿病血管并发症发生的因素。结论:牙周病与糖尿病、血糖控制情况及慢性血管并发症密切相关。Objective：To explore the relationship between periodontal disease and chronic vasculopathy complications in type 2 diabetes. Methods：A retrospective study was untaken in 166 diabetic patients with periodontal examinations and chronic vasculopathy complications. The patients were divided into four groups, diabetic non-vasculopathy complications （A）, diabetic microvascular complications （B）,diabetic macrovascular complications （C）,diabetic microvascular and macrovascular complications （D）,meanwhile,54 healthy people were selected as control group. The periodontal pocket depth （PD）,gingivitis index （GI） and clinical attachment loss（CAL） were recorded. Results：（1） PD,GI and CAL were significantly increased in groups with diabetes（P〈0.05）. The levels of PD , GI and CAL were higher in diabetic complication group than those in diabetic group without complications（P〈0.05）. （2）The level of HbA1c was positively correlated with PD, GI and CAL（r = 0.617, 0.593 and 0.468, P 〈0.01）. （3）The Logistic analysis showed that PD, GI and CAL were significantly related to the chronic vasculopathy complications in type 2 diabetes. Conclusion：There may be a correlation between periodontal disease and chronic vasculopathy complications in type 2 diabetes.

关 键 词：糖尿病 2型 糖尿病血管病变 牙周疾病 LOGISTIC模型 

分 类 号：R587.2[医药卫生—内分泌]