3-取代-6-甲氧基-7-羟基-4H-色烯-4-酮的合成及其异常反应  

Synthesis of 3-Substituent-6-methoxy-7-hydroxy-4H-chromen-4-ones and the Related Unexpected Reactions

作　　者：李涵彬[1] 任毅[1] 张倩[1] 

机构地区：[1]复旦大学药学院药物化学教研室,上海201203

出　　处：《有机化学》2011年第4期563-566,共4页Chinese Journal of Organic Chemistry

基　　金：创新药物平台(No.2009ZX09301-011)资助项目

摘　　要：报道了3-位分别为苯基、氢原子以及卤素等不同取代的4H-色烯-4-酮类化合物的合成方法,并探讨和阐明了一些意外产物的获得机理,不仅对该位点的进一步结构改造提供了物质基础,同时拓展了构建4H-色烯-4-酮类化合物的底物结构.Several 4H-chromen-4-ones with different substituents at 3-position, including phenyl, hydrogen and halogen were synthesized and the mechanism of the related unexpected products was discussed. This work will not only profit further modification on 3-position of parent structure but also enrich the chemical characteristics of this kind of compounds.

关 键 词：取代4H-色烯-4-酮 环合反应 异常反应机理 

分 类 号：O621.2[理学—有机化学]