机构地区:[1]南京医科大学附属淮安第一人民医院CT室,223300
出 处:《中华放射学杂志》2011年第3期229-234,共6页Chinese Journal of Radiology
摘 要:目的探讨双源CT双能量头部虚拟平扫(VNC)的图像质量和临床应用价值。方法对62例临床怀疑脑血管病变的患者,使用双源CT进行头部常规平扫(CNC)和双能量CTA检查,利用双能量软件得到VNC图像。比较CNC和VNC图像灰质、白质、脑脊液、高密度出血性和低密度缺血性病变的CT值,使用4分法对图像质量进行主观评价,比较两组图像的噪声、辐射剂量和病变检出率,使用配对t检验、Wilcoxon符号秩检验和X2检验(McNemar检验和Kappa检验)进行统计分析。结果CNC与VNC图像灰质、白质、脑脊液、高密度病变及低密度病变的CT值分别为[(43.3±1.5)和(33.2±1.3)HU,t=46.98]、[(32.9±1.3)和(28.8±1.6)HU,t=16.28I、(9.0±1.4)和(5.3±1.9)HU,t=12.41]、[(62.8±10.0)和(51.3±11.5)HU,z=-4.37]、[(20.7±4.7)和(18.0±6.9)HU,t=3.84],差异均有统计学意义(P值均〈0.01)。VNC图像噪声[(1.63±0.34)HU]大于CNC图像[(0.99±0.18)HU](Z=-6.41,P〈0.01)。VNC图像有效剂量[(0.53±0.08)rosy]低于CNC[(1.37±0.23)rosy](Z=-6.45,P〈0.01)。CNC和VNC图像噪声、颅底伪影、灰白质对比、高密度和低密度病变显示的主观评分分别为(3.9±0.3)和(2.7±0.5)分、(3.7±0.5)和(2.4±0.9)分、(3.3±0.6)和(1.3±0.5)分、(4.0±0.0)和(3.0±0.4)分、(3.9±0.3)和(3.2±0.8)分,VNC图像噪声与颅底伪影的评分较CNC图像低(Z值分别为-6.84、-6.15,P值均〈0.01),灰白质对比、高密度和低密度病变显示低于CNC图像(Z值分别为-7.01、-4.52和-3.12,P值均〈0.01)。在个体水平,VNC图像显示高密度出血性病变29例,无假阳性和假阴性病例,敏感性、特异性、阳性预测值和阴性预测值均为100.0%(29/29、33/33、29/29、3Objective To investigate image quality and clinical value of dual-source dual energy virtual non-contrast ( VNC ) CT of the head. Methods Sixty-two patients suspected of cerebrovascular diseases underwent conventional non-contrast (CNC) CT and dual energy CTA examination of the head with dual-source CT. Virtual non-contrast images were reconstructed using dual energy software. The CT values of gray matter, white matter, cerebrospinal fluid, hyperdense hemorrhagic lesion and hypodense ischemic lesion were compared between CNC and VNC images. A four-score scale was used to assess image quality subjectively. Image noise, radiation dosage and detection rate were compared between CNC and VNC images. Paired t test, Wilcoxon signed ranks test and Chi-square test (McNemar test and Kappa test) were used. Results The CT value on CNC and VNC images, were (43.3 ± 1.5) and (33.2 ± 1.3 ) HU for gray matter (t=46.98, P〈0.01), (32.9 ±1.3) and (28.8 ±1.6) HU for white matter(t=16.28, P〈 0.01), (9.0 ± 1.4) and (5.3 ± 1.9) HU for cerebrospinal fluid (t =12.41, P〈0.01),(62.8 ± 10.0) and (51.3 ± 11.5) HU for hyperdense lesion (Z = -4.37, P 〈 0.01), (20.7 ±4.7) and (18.0 ±6.9) HU for hypodense lesion ( t = 3.84, P 〈 0. 01 ), respectively. VNC images [ ( 1.63 ± 0.34) HUI had more noise than CNC images [(0.99 ±0.18) HU] (Z= -6.41, P〈0.01). VNC [ (0. 53 ± 0. 08) mSv] had less effective dose than CNC [ (1.37 ± 0. 23) mSv] (Z = -6. 45, P 〈 0. 01 ). In subjective assessment, VNC images had more noise ( 2. 7 ± 0. 5 for VNC and 3.9 ± 0. 3 for CNC, Z = -6. 84, P 〈 0. 01 ) and skull base-related artifacts (2.4 ± 0. 9 for VNC and 3.7 ± 0. 5 for CNC, Z = -6. 15, P 〈 0. 01 ) than CNC images. The gray/white matter contrast (1.3 ± 0. 5 for VNC and 3.3 ± 0. 6 for CNC, Z = - 7.01, P 〈 0. 01 ), hyperdense lesion display (3.0 ± 0.4 for VNC and 4. 0 ± 0. 0 for CNC,Z = - 4. 52, P 〈 0. 01 ) and hypodens
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