A Fast and Highly Efficient Protocol for Reductive Amination of Aromatic Aldehydes Using NaBH4 and Isoxazole Amines in an Ionic Liquid Medium  

作　　者：Eligeti, Rajanarendar Atthunuri, Siva Rami Reddy Samala, Raju Shaik, Firoz Pasha Govardhan Reddy 

机构地区：[1]Department of Chemistry, Kakatiya University, Warangal, 506009 Andhra Pradesh, India

出　　处：《Chinese Journal of Chemistry》2011年第4期769-772,共4页中国化学（英文版）

摘　　要：Reductive amination of aromatic aldehydes using NaBH4 and isoxazole amines is carried out in a Bronsted acidic ionic liquid 1 -methylimidazolium tetrafluoroborate [（HMIm）BF4]. The ionic liquid plays dual roles of solvent as well as catalyst for the efficixcellent yields without any undesired side product formation. The newly synthesized compoundsent transformation of aromatic aldehydes to heterocyclic substituted amines in e （3, 6 and 7） were characterized by IR, 1H NMR and mass spectral techniques.Reductive amination of aromatic aldehydes using NaBH4 and isoxazole amines is carried out in a Bronsted acidic ionic liquid 1 -methylimidazolium tetrafluoroborate [（HMIm）BF4]. The ionic liquid plays dual roles of solvent as well as catalyst for the efficixcellent yields without any undesired side product formation. The newly synthesized compoundsent transformation of aromatic aldehydes to heterocyclic substituted amines in e （3, 6 and 7） were characterized by IR, 1H NMR and mass spectral techniques.

关 键 词：ionic liquid green chemistry reductive amination 1-methylimidazolium tetrafluoroborate isoxazole amine 

分 类 号：O646.1[理学—物理化学] TQ463.4[理学—化学]