分枝杆菌多糖免疫调节剂研究进展  

Research Progress of Mycobacterium Polysaccharide Immunomodulator

作　　者：周莉婷[1,2] 赵晶晶 吴彦卓 杨仲璠 姚文兵[1] 徐明波 

机构地区：[1]中国药科大学生命科学与技术学院,江苏南京210009 [2]北京双鹭药业股份有限公司,北京100041

出　　处：《药物生物技术》2011年第2期176-179,共4页Pharmaceutical Biotechnology

摘　　要：多种多糖类物质的免疫调节作用已得到证实,并应用于多种疾病的预防和治疗。非致病性分枝杆菌制剂及从中提取的多糖成分(卡介菌制剂、母牛分枝杆菌制剂、草分枝杆菌制剂、卡介菌多糖核酸、分枝杆菌多糖等),都具有一定的免疫调节作用,主要用于结核、癌症、呼吸道感染等免疫功能低下引起的疾病的辅助治疗。It has been confirmed that polysaccharides have immunological effect,and they have been used to prevent and treat many kinds of diseases.Non-pathogenic Mycobacteria preparation and polysaccharides extracted from them also have immunological effect,such as BCG vaccine,Mycobacterium vaccae for injection,Mycobacterium phlei F.U.36 injection,BCG-PSN,Mycobacterial polysaccharides（MPS）,which have been tried as immunomodulator in diseases related to low immune function,involving tuberculosis,cancer,respiratory tract infection,etc.

关 键 词：多糖 分枝杆菌 免疫调节剂 

分 类 号：Q239[生物学—细胞生物学]