216例男性不育症精液检验与血清中抗精子抗体的关系  

The correlation between the semen routine indicators and serum anti-sperm antibody level in infertility patients

作　　者：黎兴盛 鲍琳 杨春 周伟华 杨舒婷 

机构地区：[1]江西省宜春市妇幼保健院检验科,江西宜春336000

出　　处：《实验与检验医学》2011年第2期121-122,148,共3页Experimental and Laboratory Medicine

基　　金：江西省科技支撑计划(2009BSA12400)

摘　　要：目的了解不育症患者精液常规指标和血清中抗精子抗体(AsAb)水平的关系。方法常规检验精子密度、精子活动力、精子活动百分率、精液中的白细胞、精液量与液化时间及pH值等,酶联免疫吸附试验检测血清AsAb。结果对216例不育症患者的检测中,精子密度小,活动力差,精液中WBC数多,其血清中的AsAb阳性率增高;死精与无精患者AsAb阳性率高达81.8%和76.9%;AsAb阳性的高低与精液量、液化时间与pH值3项指标无直接的关系。结论不育症患者精液中AsAb阳性率的高低对精子密度、精子活动力、精子活动百分率产生很大的影响,测定AsAb有助于查找男性不育症患者的病因。Objective To understand the correlation between the semen indicators and serum anti-sperm antibody（AsAb） level in the infertility patients.Methods Related semen indicators were detected by routine test.Serum anti-sperm antibody was tested by enzyme-linked immunosorbent assay.Results Of 216 infertility patients,the cases with low sperm density,poor activity and increased WBC in semen showed a high serum AsAb positive rate.The positive rates of surum AsAb in the patients with no sperm and dead sperm were 81.8% and 76.95% respectively.Serum AsAb positive rate was no direct relationship with the volume,liquefaction time and pH of semen.Conclusions Serum AsAb of infertility patients may affect the quantity,motility and activity percentage of sperm.AsAb detection is helpful to finding the cause of male infertility.

关 键 词：不育症 抗精子抗体 精子密度 精子活动力 

分 类 号：R446.19[医药卫生—诊断学] R446.62[医药卫生—临床医学]