不同地区孕妇缺碘状况及干预补碘效果的调查研究  

Investigation on iodine deficiency situation of pregnant women in various areas and effect of iodine supplementation intervention

作　　者：杨强[1] 李凡卡[1] 王立杰[1] 张凯[1] 韩菲[1] 

机构地区：[1]新疆生产建设兵团疾病预防控制中心,乌鲁木齐830002

出　　处：《疾病预防控制通报》2011年第2期11-13,16,共4页Bulletin of Disease Control & Prevention(China)

基　　金："十一五"国家科技支撑计划项目(2006BAI06B05)

摘　　要：目的研究新疆生产建设兵团3个不同地区(轻度、中度、重度缺碘地区)4组孕妇碘营养水平,及采取干预补碘前后尿碘的变化,分析评价干预效果。方法选择碘盐覆盖率、尿碘水平不同的三类缺碘地区,调查孕妇服碘化油胶丸前后的尿碘水平。结果干预前4组孕妇的尿碘中位数分别为119.90、147.20、214.00和167.10μg/L,尿碘值<100μg/L的比例分别是30.0%、4.3%、42.9%和20%;干预后1个月4组孕妇中位数分别为172.25、148.70、164.50和229.80μg/L;尿碘值<100μg/L的比例分别是25.0%、22.2%、19.5%和0;干预后3个月中位数分别为150.00、103.60、176.60和219.60μg/L;尿碘值<100μg/L的比例分别是25.0%、47.8%、13.8%和13.8%;干预后6个月中位数分别为119.90、147.20、214.00和167.10μg/L;尿碘值<100μg/L的比例分别是25.0%、15.4%、13.8%和0;干预后9个月中位数分别为173.95、185.20、208.50和262.21μg/L;尿碘值在<100.0μg/L的比例分别是21.9%、10.3%、26.1%和0。结论干预补碘可以使缺碘地区的孕妇尿碘中位数向高值偏移,能明显改善碘缺乏地区碘营养状况;在中度缺碘地区的孕妇用较小剂量200mg能满足自身的碘需求,在重度缺碘地区的孕妇用较大剂量400mg能满足自身的碘需求,特别是在干预后1个月、3个月,干预措施对尿碘的升高影响明显。Objective To research iodine nutrition level of four groups of pregnant women in 3 various areas（with iodine deficiency of mild,moderate and severe degrees） of Xinjiang Production and Construction Corps,and change of urine iodine before and after intervention of iodine supplementation,to analyze intervention effect.Methods The area of 3rd type with iodine deficiency and various coverage rates of iodine salt and urine iodine level were selected to investigate the urine iodine level of the pregnant women before and after taking iodinated oil soft capsules.Results Median of urine iodine of the four groups of the pregnant women before intervention was 119.90,147.20,214.00 and 167.10 μg/L,respectively,with proportion of urine iodine number 100 μg/L of 30.0%,,4.3%,42.9% and 20%,respectively.The median was 172.25,148.70,164.50 and 229.80 μg/L,with the proportion of 25.0%,22.2%,19.5% and 0 after intervention 1 month;and 150.00,103.60,176.60 and 219.60 μg/L,with the proportion of 25.0%,47.8%,13.8% and 13.8% after intervention 3 months;119.90,147.20,214.00 and 167.10 μg/L,with the proportion of 25.0%,15.4%,13.8% and 0 after intervention 6 months;173.95,185.20,208.50 and 262.21 μg/L,with the proportion of 21.9%,10.3%,26.1% and 0 after intervention 9 months.Conclusions Intervention with iodine supplementation can make median of urine iodine of pregnant women drift to high value,and significantly improve the Abstract：Objective To research iodine nutrition level of four groups of pregnant women in 3 various areas（with iodine deficiency of mild,moderate and severe degrees） of Xinjiang Production and Construction Corps,and change of urine iodine before and after intervention of iodine supplementation,to analyze intervention effect.Methods The area of 3rd type with iodine deficiency and various coverage rates of iodine salt and urine iodine level were selected to investigate the urine iodine level of the pregnant women before and after taking iodinated oil soft capsules.Results Median of urine iodine of the four g

关 键 词：孕妇 尿碘 干预 补碘 

分 类 号：R591.1[医药卫生—内科学] R151.42[医药卫生—临床医学]