气相色谱/质谱联用检测唇用产品中二甘醇的残留  

The Determination of Residual Diethylene Glycol in Lipstick by Gas Chromatography/Mass Spectrometry

作　　者：余雯静[1] 郑晨[1] 赵玉兰[1] 沈洁[1] 

机构地区：[1]苏州出入境检验检疫局,苏州215104

出　　处：《香料香精化妆品》2011年第2期35-37,共3页Flavour Fragrance Cosmetics

摘　　要：建立了气相色谱/质谱联用(GC/MS)检测唇膏中二甘醇残留量的方法。样品经海砂研磨均匀、无水硫酸钠除水后,以甲醇超声提取,滤液直接检测。采用外标法,选择离子定量。二甘醇在10.0～1000.0mg/kg浓度范围内线性关系良好,相关系数(R2)为0.9994。在10～1000mg/kg添加水平的平均回收率为92.5%～106.9%,相对标准偏差(RSD)为3.5%～4.6%。实验表明,该方法适用于唇膏等化妆品中二甘醇残留量的检测。The method for determination of residual diethylene glycol in lipstick by gas chromatography/mass spectrometry （GC/MS） was established. After grinding by sea sand, removing moisture by anhydrous sodium sulfate, the sample was ultrasonic extracted with methanol, then it was detected directly. Using external standard method and selecting ion quantification, the diethylene glycol had good linear relationship within concentrations between 10.0 to 1000. 00 mg/kg. And the correlation coefficient （R2） was 0. 999 4. In 10 - 1 000 mg/kg, the average recovery of added level was 92.5% - 106.9% and the relative standard deviation （RSD） was 3.5% - 4.6%. The results showed that the method is suitable for determination residual diethylene glycol in lipstick and other cosmetics.

关 键 词：二甘醇 气相色谱/质谱法 唇膏 化妆品 

分 类 号：TQ658[化学工程—精细化工]