DMRT1 at the border between mitosis and meiosis  

作　　者：Jeremy Don Uri Nir Haim Breitbart 

机构地区：[1]The Mina and Everard Goodman Faculty of LifeSciences, Bar-Ilan University, Ramat-Gan 52900, Israel

出　　处：《Asian Journal of Andrology》2011年第2期189-190,共2页亚洲男性学杂志（英文版）

摘　　要：In males, sperm production begins at puberty and lasts throughout reproduct-ire life. This implies that a population of germ stem cells/progenitors must be main- tained, amplified and differentiate throughout life to enable the continuous supply of sperm. Spermatogenesis is indeed divided into three phases： a proliferative phase, a meiotic phase and a postmeiotic spermio- genic phase. In the proliferative phase, undifferentiated spermatogonia stem cells are divided to maintain the principle undiffer- entiated stern cell population on the one hand, and on the other hand to amplify and differentiate a fraction of the spermatogonia into primary spermatocytes.In males, sperm production begins at puberty and lasts throughout reproduct-ire life. This implies that a population of germ stem cells/progenitors must be main- tained, amplified and differentiate throughout life to enable the continuous supply of sperm. Spermatogenesis is indeed divided into three phases： a proliferative phase, a meiotic phase and a postmeiotic spermio- genic phase. In the proliferative phase, undifferentiated spermatogonia stem cells are divided to maintain the principle undiffer- entiated stern cell population on the one hand, and on the other hand to amplify and differentiate a fraction of the spermatogonia into primary spermatocytes.

分 类 号：Q253[生物学—细胞生物学] Q954.434