An efficient route for synthesis of 2-alkylamino benzo[b]thieno[3,2-d]pyrimidin-4(3H)-one  

作　　者：Min Hui Cao Sheng Zhen Xu Chang Shui Chen 

机构地区：[1]College of Basic Science,Huazhong Agricultural University,Wuhan 430070,China

出　　处：《Chinese Chemical Letters》2011年第4期443-446,共4页中国化学快报（英文版）

基　　金：supported by Huazhong Agricultural University Scientific & Technological Self-innovation Foundation(Nos.2007XRC064 and 2008XKJC005)

摘　　要：The carbodiimide 2,obtained from the aza-Wittig reactions of iminophosphorane 1 with alkyl isocyanates,reacted with primary amino to give 2-alkylamino benzo[b]thieno[3,2-d]pyrimidin-4（3H）-ones 4 and 5.The formation mechanism of the title compounds has been investigated.The carbodiimide 2,obtained from the aza-Wittig reactions of iminophosphorane 1 with alkyl isocyanates,reacted with primary amino to give 2-alkylamino benzo[b]thieno[3,2-d]pyrimidin-4（3H）-ones 4 and 5.The formation mechanism of the title compounds has been investigated.

关 键 词：CARBODIIMIDES Aza-Wittig reaction IMINOPHOSPHORANE ISOCYANATES Synthesis 

分 类 号：O626[理学—有机化学] O626.12[理学—化学]