葡萄球菌性烫伤样皮肤综合征12例临床分析  

作　　者：张侃[1] 刘喜[1] 于红艳[1] 罗勇[1] 

机构地区：[1]深圳市宝安区妇幼保健院,518133

出　　处：《中国社区医师（医学专业）》2011年第13期189-190,共2页

摘　　要：目的:了解葡萄球菌烫伤样皮肤综合征(SSSS)的临床特点及治疗措施。方法:回顾性分析12例1个月～5岁小儿SSSS的临床表现、治疗措施及其疗效。结果:全部患者均有泛发性红斑及皮肤触痛,所有病例均有表皮剥脱及尼氏征阳性。12例做创面分泌物细菌培养,发现2例金黄色葡萄球菌阳性。经及时使用抗生素(头孢类抗生素)、适当的局部处理使裸露创面在5～7天完全愈合而出院。结论:SSSS好发于新生儿及婴幼儿。早期诊断、及时应用耐β-内酰胺酶抗生素或第3代头孢菌素及适当的局部处理是治疗的关键。Objective： To study clinical characteristics and treatment regimen of staphylococcal scalded skin syndrome （SSSS） in young children. Methods： Twelve patients with SSSS aged 1 -3 years were collected from January 2002 to October 2006, and their clinical manifestations, treatment regimen and thera-peutic efficacy were analysed retrospectively. Results：There were generalised erythema and skin tenderness in all cases. All had positive Nikolsky＇s sign. Skin culture was made in 12 cases, and Staphylococcus aurous was isolated from only two. The denuded surface healed in 5 -7 days after managed with prompt antibiotics （combined oxacillin with three replace cephalosporin）and appropriate topical treatment, and all patients were quite recovered. Conclusion： SSSS usually occurs in neonates,infants and young children, Early diagnosis, timely therapy combined oxacillin with three replace cephalosporin and suitable topical treatment are the pivotal regimen for this entity.

关 键 词：金葡菌性烫伤样皮肤综合征 金黄色葡萄球菌 早期诊断治疗 

分 类 号：R753[医药卫生—皮肤病学与性病学]