甘露醇和山梨醇鉴别反应原理的实验研究  

Study on the mechanisms of identifying mannitol and sorbitol

作　　者：宋丽英[1] 金恒启[2] 王希军[1] 张如春[1] 

机构地区：[1]白求恩军医学院,石家庄050081 [2]石家庄医学高等专科学校,050081

出　　处：《白求恩军医学院学报》2011年第2期83-84,共2页Journal of Bethune Military Medical College

摘　　要：目的阐明甘露醇和山梨醇鉴别反应的原理。方法按药典鉴别方法,采用紫外分光光度法测定有色溶液的吸光度。结果甘露醇与Fe^(3+)在碱性条件下形成的化合物稳定性非常强,加入过量强碱也不会使其分解生成溶解度极小的氢氧化铁沉淀。山梨醇在浓硫酸作用下生成黄色溶液,对紫外光吸收峰值在260～285 nm波长范围内。结论用三氯化铁鉴别甘露醇,形成Fe-甘露醇螯合物结构为八面体构型,稳定性强;用儿茶酚鉴别山梨醇,在浓硫酸作用下,先生成糠醛衍生物,再与儿茶酚生成具有醌式结构的化合物,显示颜色。Objective To elucidate the mechanisms of identifying mannitol and sorbitol.Methods According to identifying methods in pharmacopoeia of China,absorbency of the color solution was determined with ultraviolet spectrophotometry.Results Mannitol turned to stable compound with Fe^（3＋） in alkaline solution.It could not decompose to ironic hydroxide with infinitesimal solubility in excess strong base solution.In concentrated sulfuric acid,sorbitol turned to yellow solution with peak absorption in wavelength of 260 nm to 285 nm.Conclusion Identifying mannitol with iron chloride,ferric-mannitol chelate is octahedral structure with better stability.In concentrated sulfuric acid,sorbitol turns to furfural derivant and then to quinonoid compound with catechol.

关 键 词：甘露醇 山梨醇 三氯化铁 儿茶酚 

分 类 号：O623.413[理学—有机化学]