影响门脉高压β受体阻滞剂应答率的多因素回归研究  

Multivariate regression analysis of factors influencing β -blocker response rates for patients with portal hypertension

作　　者：林奕芬[1] 郑灿滨[2] 郑晓璇[1] 

机构地区：[1]汕头市中心医院中山大学附属汕头医院内科,515031 [2]南方医科大学2010级第一临床医学院,510515

出　　处：《国际医药卫生导报》2011年第7期775-777,共3页International Medicine and Health Guidance News

基　　金：基金项目：汕头市重点科技计划资助（汕府科2010[63]）

摘　　要：目的从护理学角度探讨影响门脉高压患者服用β受体阻滞剂应答率的相关因素，通过多因素分析研究法，寻找独立影响指标，为针对性护理干预提供科学依据。方法60例有用药指征的门脉高压患者常规服用3个月后依应答与否分为应答组与无应答组，采用社会支持量表及自拟的患者就医行为调查表，单因素回归分析与应答率相关的因素，在此基础上，采用多元回归分析法，筛选影响应答率的独立影响指标。结果单因素研究分析发现，社会支持度总分及三个维度中的主观支持与对支持的利用度在应答组与无应答组间有统计学差异，患者家属对疾病防治知识的了解在两组问也有差别，经多元回归分析，患者对支持的利用度与亲属对疾病的了解程度为独立影响因素。结论提高门脉高压患者对社会支持利用度的资源利用、加强患者家属对疾病防治的宣教是提高应答率的关键。Objective To analyze factors influencing β -blocker responds rates on patients with portal hypertension and to investigate the independent factors on basis of multivariate analysis in an aim to offer objective guideline for nursing intervention. Methods 60 cases of portal hypertension having indication of taking inderal were analyzed after 3 months routine inderal taking. Social support rating scale and self-designed questionale were collected and analyzed. Multivariate regression analysis was performed to establish the independent influencing factors. Results comparing to those with non-response patients, total score of social support was higher in those with response patients, among which objective support and utilization degree scores were higher with statistics significance. Multifactorial analysis showed utilization degree scores and knowledge about the disease and related medicine acquired by patient＇s relatives are the independent factors influencing the response rates. Conclusion much attention should be drawn to the utilization degree from social support and the knowledge of the disease and related medicine acquired by the patient＇s relatives in dealing with portal hypertension patients taking β -blocker.

关 键 词：门脉高压 Β受体阻滞剂 应答率 社会支持度 

分 类 号：R473[医药卫生—护理学]