应用64排螺旋CT评价阿托伐他汀对冠状动脉斑块的影响  

Evaluation of Influence of Artovastatin on Coronary Artery Atheromatous Plaque by 64 Slice Spiral CT

作　　者：李学文[1] 赵季红[1] 姜铁民[1] 冯凯琳[2] 顾欣[2] 孟凡超[1] 宗洁[2] 

机构地区：[1]武警医学院附属医院心内科,天津300162 [2]武警医学院附属医院放射科,天津300162

出　　处：《医疗卫生装备》2011年第4期69-71,共3页Chinese Medical Equipment Journal

基　　金：武警医学院院级课题(WJ200812)

摘　　要：目的:评价阿托伐他汀对冠状动脉粥样斑块的影响。方法:对43例经64排螺旋CT冠脉CTA检测出的粥样斑块患者,给予阿托伐他汀20 mg/d口服,6个月后复查粥样斑块情况。结果:43例患者有119支冠状动脉存在132个粥样斑块,治疗后各种斑块大小有不同程度的下降,其中脂质斑块下降幅度16.4%,纤维斑块下降幅度8.1%,混合斑块下降幅度10.7%,而钙化斑块下降幅度不明显。结论:阿托伐他汀可逆转或稳定冠脉粥样斑块,从而降低急性冠状动脉事件的发生;64排螺旋CT可定量评价粥样斑块的变化,为临床治疗提供客观依据。Objective To evaluate the influence of artovastatin on coronary artery atheromatous plaque.Methods 43 cases of coronary artery atheromatous plaque examined with 64 slice spiral CT and retrospectively ECG gated technology,received artovastatin tablets（20 mg/d） for six months,and the atheromatous plaque were scanned again.Results Of the 43 cases in this study,132 atheromatous plaques occurred in 119 coronary artery branches.The sizes of all plaques had different degrees of descent after the treatment.The rate of descent was 16.4% in lipoid plaques,8.1% in fibrous plaques,10.7% in 13 plaques.Conclusion Artovastatin can reverse and stabilize the Coronary artery atheromatous plaque,and reduce the occurrence of acute coronary artery affairs.64 slice spiral CT can quantitatively evaluate the changes of atheromatous plaque.It provides objective basis for the clinic treatment.

关 键 词：易损斑块 阿托伐他汀 64排螺旋CT 

分 类 号：R541.4[医药卫生—心血管疾病]